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[恶性肿瘤所致气管支气管病变的钕-钇铝石榴石激光治疗]

[Nd-YAG laser therapy of tracheobronchial lesions by malignant tumor].

作者信息

Kikuchi K, Kakizaki T, Sawafuji M, Hangai N, Yamamoto T, Kobayashi T, Watanabe M, Kawamura M, Kato R, Kobayashi K

机构信息

Department of Surgery, Keio University School of Medicine.

出版信息

Kyobu Geka. 1992 Jan;45(1):14-8.

PMID:1735932
Abstract

Thirty-seven patients with tracheobronchial lesions by malignant tumor were treated with Nd-YAG laser. Thirty-seven patients were twenty-three males and fourteen females and ages ranged from 34 to 79 years. Diseases included were primary tracheal tumor in 3 cases, lung cancer in 16 (8 squamous cell carcinoma, 5 adenocarcinoma, 2 large cell carcinoma, 1 small cell carcinoma), cancer of adjacent organs in 9 (5 thyroid cancers, 4 esophageal cancers), and metastatic cancer to the lung or mediastinal lymph nodes in 9 (4 renal cell carcinoma, 2 thyroid cancer, one patient respectively, colon cancer and breast cancer). Intermittent irradiation of YAG laser was done for 0.5 second at 30-40 Watt through flexible bronchoscope under local anesthesia. It was repeated 1 to 41 times (mean 4.1 times) and energy amount was 148 Joules to 18,513 Joules (mean 3,305 J). The result was; stenosis disappeared in 22 cases (59.4%), improved in 14 (37.8%), and in one case YAG laser therapy discontinued due to intractable bleeding. The Nd-YAG laser therapy for tracheobronchial lesions by malignant tumor is very useful to improve dyspnea or atelectasis.

摘要

37例气管支气管恶性肿瘤病变患者接受了Nd-YAG激光治疗。37例患者中,男性23例,女性14例,年龄在34至79岁之间。疾病包括原发性气管肿瘤3例,肺癌16例(8例鳞状细胞癌、5例腺癌、2例大细胞癌、1例小细胞癌),邻近器官癌9例(5例甲状腺癌、4例食管癌),肺或纵隔淋巴结转移癌9例(4例肾细胞癌、2例甲状腺癌、各1例结肠癌和乳腺癌)。在局部麻醉下,通过可弯曲支气管镜以30 - 40瓦的功率对YAG激光进行0.5秒的间歇照射。重复照射1至41次(平均4.1次),能量为148焦耳至18513焦耳(平均3305焦耳)。结果是:22例(59.4%)狭窄消失,14例(37.8%)改善,1例因难以控制的出血而停止YAG激光治疗。Nd-YAG激光治疗气管支气管恶性肿瘤病变对于改善呼吸困难或肺不张非常有用。

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