哮喘患儿的临床症状与“超说明书”用药
Clinical symptoms and 'off-label' prescribing in children with asthma.
作者信息
McCowan Colin, Hoskins Gaylor, Neville Ron G
机构信息
Tayside Centre for General Practice, University of Dundee, Dundee, UK.
出版信息
Br J Gen Pract. 2007 Mar;57(536):220-2.
Abstract
A UK-wide database of structured asthma review consultations was used to investigate the prevalence of 'off-label' anti-asthma prescriptions in relationship to clinical symptoms of asthma control. The 1050 children (6.1%) aged 16 years or under issued with an off-label prescription reported more nighttime, daytime and activity asthma symptoms, and used more short-acting beta(2)-agonist medication than their peers. Off-label prescribing for children with asthma in UK primary care is associated with worse levels of self-reported asthma control.
摘要
一个覆盖全英国的结构化哮喘复诊咨询数据库被用于调查“超说明书”抗哮喘处方的流行情况及其与哮喘控制临床症状的关系。1050名16岁及以下开具了超说明书处方的儿童（占6.1%）报告称，他们夜间、白天和活动时的哮喘症状更多，且比同龄人使用了更多的短效β2受体激动剂药物。在英国初级医疗保健中，给哮喘儿童开超说明书处方与自我报告的哮喘控制水平较差有关。
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