Qiu Xue-feng, Dong Nian-guo, Pan Tie-cheng, Wei Xiang, Shi Jia-wei
Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Zhonghua Wai Ke Za Zhi. 2006 Nov 15;44(22):1538-40.
To summarize the experience of combined off-pump coronary artery bypass grafting (OPCAB) and pulmonary resection.
Seven patients with unstable angina or a history of myocardial infarction and pulmonary disease underwent combined OPCAB and pulmonary resection. All of them underwent coronary angiography, and neither coronary angioplasty nor stenting was feasible. OPCAB preceded the lung resections. The preferred approach to the heart and lung was by sternotomy. Left upper lobectomy was performed in 2 patients, right upper lobectomy was performed in 1 patient, right lower lobectomy was performed in 1 patient, right upper and middle bilobectomy was performed in 1 patient, left lung volume reduction surgery (LVRS) was performed in 1 patient and bilateral LVRS was performed in 1 patient.
There were no hospital mortality in this group of patients, however there were one late death. Sternal dehiscence occurred in 1 patient which was observed with a need for re-sternotomy and atrial fibrillation was observed in 1 patient. Five patients were diagnosed as malignant tumor by pathology test, and 2 patients were severe chronic obstructive pulmonary disease (COPD). Follow-up ranging from 2 months to 31 months was available for these patients. None of the patients showed evidence of myocardial ischemia after surgery. In one patient, who underwent right upper and middle bilobectomy, local recurrence was found at 19 months after surgery.
OPCAB carried out simultaneously with lung resection is a safe and effective approach in patients diagnosed with concomitant coronary artery and pulmonary disease. OPCAB may decrease the incidence of postoperative complications.
总结非体外循环冠状动脉旁路移植术(OPCAB)与肺切除术联合应用的经验。
7例患有不稳定型心绞痛或有心肌梗死病史及肺部疾病的患者接受了OPCAB与肺切除术联合治疗。所有患者均接受了冠状动脉造影,且冠状动脉血管成形术或支架置入术均不可行。先进行OPCAB,再进行肺切除术。心脏和肺部的首选手术入路是胸骨正中切口。2例行左上肺叶切除术,1例行右上肺叶切除术,1例行右下肺叶切除术,1例行右上中叶双叶切除术,1例行左肺减容手术(LVRS),1例行双侧LVRS。
该组患者无院内死亡,但有1例晚期死亡。1例患者发生胸骨裂开,需再次行胸骨切开术,1例患者出现心房颤动。5例患者经病理检查诊断为恶性肿瘤,2例患者为重度慢性阻塞性肺疾病(COPD)。这些患者的随访时间为2个月至31个月。术后无一例患者出现心肌缺血迹象。1例接受右上中叶双叶切除术的患者在术后19个月发现局部复发。
对于诊断为合并冠状动脉和肺部疾病的患者,OPCAB与肺切除术同时进行是一种安全有效的方法。OPCAB可能会降低术后并发症的发生率。