Shen Chenghua, Choi Min-Ho, Bae Young Mee, Yu Gui, Wang Shuhua, Hong Sung-Tae
Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, Republic of Korea, and Department of Internal Medicine, Heilongjiang Provincial Zhaoyuan People's Hospital, Zhaoyuan, People's Republic of China.
Am J Trop Med Hyg. 2007 Mar;76(3):603-5.
A 35-year-old Chinese man was administered praziquantel for clonorchiasis, and 30 minutes later he experienced a sudden onset of itching urticaria over his entire body with dyspnea, palpitation, and dizziness. The patient had no recent medication history except for the praziquantel. He was diagnosed as having an anaphylactic reaction with skin eruptions induced by praziquantel. His symptoms subsided after a stomach wash and the administration of anti-anaphylactic medication in emergency department of a regional hospital in the People's Republic of China. The immediate type of hypersensitive reaction to praziquantel is plausible, and this reaction should be considered for praziquantel therapy.
一名35岁的中国男性因华支睾吸虫病接受吡喹酮治疗，30分钟后，他突然全身出现瘙痒性荨麻疹，并伴有呼吸困难、心悸和头晕。除吡喹酮外，该患者近期无其他用药史。他被诊断为吡喹酮诱发的过敏性反应伴皮疹。在中国一家地区医院的急诊科进行洗胃并给予抗过敏药物治疗后，他的症状有所缓解。吡喹酮引起速发型超敏反应是有可能的，在吡喹酮治疗时应考虑到这种反应。
