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[严重创伤后常规参数和实验室参数的预后价值。一项关于空中救援患者的前瞻性临床前-临床研究]

[Prognostic value of routine parameters and laboratory parameters after major trauma. A prospective preclinical-clinical study of air rescue patients].

作者信息

Lackner C K, Burghofer K, Stolpe E, Schlechtriemen T, Mutschler W E

机构信息

Institut für Notfallmedizin und Medizinmanagement, Klinikum der Universität München, Schillerstr. 53, 80336, München, Germany.

出版信息

Unfallchirurg. 2007 Apr;110(4):307-19. doi: 10.1007/s00113-006-1216-0.

Abstract

In this prospective study, 273 air rescue patients with major blunt trauma were followed throughout their prehospital and clinical management. A blood sample was taken upon arrival and data acquired at three defined time points. With these data, for the first time a prognosis prediction model with prehospital and early clinical routine parameters and routine lab parameters was tested for predictive power. Coagulation test, value of base excess, Glasgow Coma Scale (GCS) value, severity of injury, and age appeared to be relevant parameters. The probability of survival after major blunt trauma decreases with increasing age and severity of injury and decreasing values in GCS, base excess, and coagulation test. These data showed that it is possible with the help of easily accessible routine parameters and routine lab parameters to predict individual survival with a high degree of accuracy of 82%.

摘要

在这项前瞻性研究中,对273例严重钝性创伤的空中救援患者在其院前和临床治疗过程中进行了全程跟踪。患者到达时采集血样,并在三个特定时间点获取数据。利用这些数据,首次对一个包含院前和早期临床常规参数以及常规实验室参数的预后预测模型进行了预测能力测试。凝血试验、碱剩余值、格拉斯哥昏迷量表(GCS)评分、损伤严重程度和年龄似乎是相关参数。严重钝性创伤后存活的概率随着年龄增长、损伤严重程度增加以及GCS评分、碱剩余值和凝血试验值降低而降低。这些数据表明,借助易于获取的常规参数和常规实验室参数,有可能以82%的高精度预测个体的存活情况。

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