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院前因素与空中医疗急救患者死亡率的相关性。

Prehospital factors associated with mortality in injured air medical patients.

机构信息

Department of Emergency Medicine, The Ohio State University, Columbus, Ohio 43210-1228, USA.

出版信息

Prehosp Emerg Care. 2012 Jan-Mar;16(1):121-7. doi: 10.3109/10903127.2011.615011. Epub 2011 Sep 29.

Abstract

BACKGROUND

Air medical transport provides rapid transport to definitive care. Overtriage and the expense and risk of transport may offset survival benefits.

OBJECTIVE

We assessed the ability of prehospital factors to predict resource need for helicopter-transported patients.

METHODS

We performed a prospective, observational cohort analysis of injured scene patients taken to one of two level I trauma centers from October 2009 to September 2010. Variables analyzed included patient demographics, diagnoses, and clinical outcomes (in-hospital mortality, emergent surgery within 24 hours, blood transfusion within 24 hours, and intensive care unit [ICU] admission ≥24 hours, as well as a combined outcome of all clinical outcomes). Prehospital variables were prospectively obtained from air medical providers at the time of transport and included past medical history, mechanism of injury, and clinical factors. We compared those variables with and without the outcomes of interest via χ(2) analysis and the Kruskal-Wallis test, where appropriate. Multivariate logistic regression identified factors associated with outcomes of interest with the intent of developing a clinical prediction tool.

RESULTS

Five hundred fifty-seven patients were transported during the study period. The majority of the patients were male (67%) and white (95%) and had an injury that occurred in a rural location (58%). Most injuries were blunt (97%), and patients had a median Injury Severity Score (ISS) of 9. The overall mortality was 4%; 48% of the patients had one of the four outcomes. The most common reasons for requesting air transport were motor vehicle collision (MVC) with high-risk mechanism (18%), MVC at a speed greater than 20 mph (18%), Glasgow Coma Scale score (GCS) less than 14 (15%), and loss of consciousness (LOC) greater than 5 minutes (15%). Factors associated with mortality were age greater than 44 years, GCS less than 14, systolic blood pressure (SBP) less than 90 mmHg, and flail chest. This model had 100% sensitivity and 50% specificity and missed no deaths. The combined endpoint of all four outcomes (death, receipt of blood, surgery, ICU admission) included intubation by emergency medical services, two or more fractures of the humerus/femur, presence of a neurovascular injury, a crush injury to the head, failure to localize to pain on examination, GCS less than 14, or the presence of a penetrating head injury. This model had a sensitivity of 57% (53%-61%) and a specificity of 78% (75%-87%).

CONCLUSIONS

Very few prehospital criteria were associated with clinically important outcomes in helicopter-transported patients. Evidence-based guidelines for the most appropriate utilization of air medical transport need to be further evaluated and developed for injured patients.

摘要

背景

空中医疗转运为患者提供快速的专科治疗。过度转运以及转运带来的花费和风险可能会抵消生存获益。

目的

我们评估了创伤现场的患者的一些因素,以预测直升机转运患者的资源需求。

方法

我们对 2009 年 10 月至 2010 年 9 月期间,从两个一级创伤中心之一转运来的创伤现场患者进行了前瞻性、观察性队列分析。分析的变量包括患者的人口统计学数据、诊断和临床结局(院内死亡率、24 小时内紧急手术、24 小时内输血、24 小时以上入住重症监护病房[ICU],以及所有临床结局的综合结局)。转运时,空中医疗服务提供者前瞻性地获得了患者的术前变量,包括既往病史、损伤机制和临床因素。我们通过 χ(2)分析和 Kruskal-Wallis 检验比较了有和没有感兴趣结局的变量,在适当的情况下进行了比较。多变量逻辑回归确定了与感兴趣结局相关的因素,目的是开发一个临床预测工具。

结果

在研究期间,共转运了 557 名患者。大多数患者为男性(67%)和白人(95%),损伤发生在农村地区(58%)。大多数损伤为钝性损伤(97%),患者的损伤严重程度评分(ISS)中位数为 9 分。总体死亡率为 4%;48%的患者有四个结局中的一个。请求空中转运最常见的原因是:高风险机制的机动车碰撞(MVC)(18%)、速度大于 20 英里/小时的 MVC(18%)、格拉斯哥昏迷量表(GCS)评分小于 14(15%)和意识丧失(LOC)大于 5 分钟(15%)。与死亡率相关的因素包括年龄大于 44 岁、GCS 评分小于 14、收缩压(SBP)小于 90mmHg 和连枷胸。该模型的敏感性为 100%,特异性为 50%,没有漏诊死亡病例。所有四个结局(死亡、输血、手术、ICU 入住)的综合终点包括:急救医疗服务时的插管、肱骨干/股骨干两处或两处以上骨折、存在神经血管损伤、头部挤压伤、不能定位到疼痛、GCS 评分小于 14 或存在穿透性头部损伤。该模型的敏感性为 57%(53%-61%),特异性为 78%(75%-87%)。

结论

很少有术前标准与直升机转运患者的临床重要结局相关。需要进一步评估和制定基于证据的空中医疗转运最恰当的使用指南,以用于创伤患者。

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