Martelli Giovanni P, Adams Michael J, Kreuze Jan F, Dolja Valerian V
Dipartimento di Protezione delle Piante e Microbiologia Applicata, Università degli Studi and Istituto di Virologia vegetale CNR, Sezione di Bari, 70126 Bari, Italy.
Annu Rev Phytopathol. 2007;45:73-100. doi: 10.1146/annurev.phyto.45.062806.094401.
The plant virus family Flexiviridae includes the definitive genera Potexvirus, Mandarivirus, Allexivirus, Carlavirus, Foveavirus, Capillovirus, Vitivirus, Trichovirus, the putative genus Citrivirus, and some unassigned species. Its establishment was based on similarities in virion morphology, common features in genome type and organization, and strong phylogenetic relationships between replicational and structural proteins. In this review, we provide a brief account of the main biological and molecular properties of the members of the family, with special emphasis on the relationships within and among the genera. In phylogenetic analyses the potexvirus-like replicases were more closely related to tymoviruses than to carlaviruses. We postulate a common evolutionary ancestor for the family Tymoviridae and the two distinct evolutionary clusters of the Flexiviridae, i.e., a plant virus with a polyadenylated genome, filamentous virions, and a triple gene block of movement proteins. Subsequent recombination and gene loss would then have generated a very diverse group of plant and fungal viruses.
柔线病毒科植物病毒包括确定的马铃薯X病毒属、柑橘衰退病毒属、葱X病毒属、香石竹潜隐病毒属、凹脉病毒属、毛病毒属、葡萄病毒属、苹果茎痘病毒属，推定的柑橘病毒属，以及一些未归类的种。该科的建立基于病毒粒子形态的相似性、基因组类型和组织的共同特征，以及复制蛋白和结构蛋白之间强大的系统发育关系。在本综述中，我们简要介绍了该科成员的主要生物学和分子特性，特别强调了各属内部和之间的关系。在系统发育分析中，类马铃薯X病毒复制酶与番茄病毒科病毒的关系比与香石竹潜隐病毒属病毒的关系更密切。我们推测番茄病毒科与柔线病毒科的两个不同进化簇有一个共同的进化祖先，即一种具有聚腺苷酸化基因组、丝状病毒粒子和移动蛋白三联基因块的植物病毒。随后的重组和基因丢失会产生一组非常多样的植物和真菌病毒。
