McCarthy Ellen P, Ngo Long H, Chirikos Thomas N, Roetzheim Richard G, Li Donglin, Drews Reed E, Iezzoni Lisa I
Division of General Medicine and Primary Care, Department of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, E/RO-139, Boston, MA 02215, USA.
Health Serv Res. 2007 Apr;42(2):611-28. doi: 10.1111/j.1475-6773.2006.00619.x.
To examine stage at diagnosis and survival for disabled Medicare beneficiaries diagnosed with cancer under age 65 and compare their experiences with those of other persons diagnosed under age 65.
Surveillance, Epidemiology, and End Results (SEER) Program data and SEER-Medicare linked data for 1988-1999. SEER-11 Program includes 11 population-based tumor registries collecting information on all incident cancers in catchment areas. Tumor registry and Medicare data are linked for persons enrolled in Medicare.
307,595 incident cases of non-small cell lung (51,963), colorectal (52,092), breast (142,281), and prostate (61,259) cancer diagnosed in persons under age 65 from 1988 to 1999. Persons who qualified for Social Security Disability Insurance and had Medicare (SSDI/Medicare) were identified from Medicare enrollment files. Ordinal polychotomous logistic regression and Cox proportional hazards regression were used to estimate adjusted associations between disability status and later-stage diagnoses and mortality (all-cause and cancer-specific).
Persons with SSDI/Medicare had lower rates of Stages III/IV diagnoses than others for lung (63.3 versus 69.5 percent) and prostate (25.5 versus 30.8 percent) cancers, but not for breast or colorectal cancers. After adjustment, they remained less likely to be diagnosed at later stages for lung and prostate cancers. Nevertheless, persons with SSDI/Medicare experienced higher all-cause mortality for each cancer. Cancer-specific mortality was higher among persons with SSDI/Medicare for breast and colorectal cancer patients.
Disabled Medicare beneficiaries are diagnosed with cancer at similar or earlier stages than others. However, they experience higher rates of cancer-related mortality when diagnosed at the same stage of breast and colorectal cancer.
研究65岁以下被诊断患有癌症的残疾医疗保险受益人的诊断阶段和生存率,并将他们的经历与其他65岁以下被诊断患有癌症的人进行比较。
1988 - 1999年的监测、流行病学和最终结果(SEER)计划数据以及SEER - 医疗保险关联数据。SEER - 11计划包括11个基于人群的肿瘤登记处,收集集水区内所有新发癌症的信息。肿瘤登记处数据与参加医疗保险的人的医疗保险数据相链接。
1988年至1999年期间,对65岁以下被诊断患有非小细胞肺癌(51,963例)、结直肠癌(52,092例)、乳腺癌(142,281例)和前列腺癌(61,259例)的307,595例新发病例进行研究。从医疗保险参保档案中识别出符合社会保障残疾保险并拥有医疗保险(SSDI/医疗保险)的人员。采用有序多分类逻辑回归和Cox比例风险回归来估计残疾状态与晚期诊断及死亡率(全因死亡率和癌症特异性死亡率)之间的调整后关联。
患有SSDI/医疗保险的人在肺癌(63.3%对69.5%)和前列腺癌(25.5%对30.8%)的III/IV期诊断率低于其他人,但乳腺癌和结直肠癌并非如此。调整后,他们在肺癌和前列腺癌晚期被诊断的可能性仍然较小。然而,患有SSDI/医疗保险的人每种癌症的全因死亡率都较高。乳腺癌和结直肠癌患者中,患有SSDI/医疗保险的人的癌症特异性死亡率更高。
残疾医疗保险受益人被诊断患有癌症的阶段与其他人相似或更早。然而,当他们在乳腺癌和结直肠癌的相同阶段被诊断时,与癌症相关的死亡率更高。