Sjöström Mats, Sennerby Lars, Nilson Hans, Lundgren Stefan
Department of Oral & Maxillofacial Surgery, Umeå University, Umeå, Sweden.
Clin Implant Dent Relat Res. 2007 Mar;9(1):46-59. doi: 10.1111/j.1708-8208.2007.00034.x.
The purpose of this study was to perform a longitudinal follow-up study of implant stability in grafted maxillae with the aid of clinical, radiological, and resonance frequency analysis (RFA) parameters.
The atrophic edentulous maxillae in 29 patients were reconstructed with free iliac crest grafts using onlay/inlay or interpositional grafting techniques. The endpoint of the resorption pattern in the maxilla determined the grafting technique used. Endosteal implants were placed after 6 months of bone-graft healing. Implant stability was measured four times using RFA: when the implants were placed, after 6 to 8 months of healing, after 6 months and 3 years of bridge loading. Individual checkups were performed at the two later RFA registrations after removal of the supraconstructions (Procera Implant Bridge, Nobel Biocare AB, Göteborg, Sweden). Radiological follow up of marginal bone level was performed annually.
Twenty-five patients remained for the follow-up period. A total of 192 implants were placed and with a survival rate of 90% at the 3-year follow up. Women and an implant position with a class 6 resorption prior to reconstruction were factors with significant increased risk for implant failure (multivariate logistic regression). Twelve of the 20 failed implants were lost before loading (early failures). The change in the marginal bone level was 0.3 +/- 0.3 mm between baseline (bridge delivery) and the 3-year follow up. The implant stability quotient (ISQ) value for all implants differed significantly between abutment connection (60.2 +/- 7.3) and after 6 months of bridge loading (62.5 +/- 5.5) (Wilcoxon signed ranks test for paired data, p=.05) but were nonsignificant between 6 months of bridge loading and 3 years of bridge loading (61.8 +/- 5.5). There was a significant difference between successful and failed implants when the ISQ values were compared for individual implants at placement (Mann-Whitney U test, p=.004). All 25 patients were provided with fixed implant bridges at the time of the 3-year follow up.
This clinical follow up using radiological examinations and RFA measurements indicates a predictable and stable long-term result for patients with atrophic edentulous maxillae reconstructed with autogenous bone and with delayed placement of endosteal implants. The ISQ value at the time of placement can probably serve as an indicator of level of risk for implant failure.
本研究旨在借助临床、放射学和共振频率分析(RFA)参数,对移植上颌骨中的种植体稳定性进行纵向随访研究。
29例患者的萎缩无牙上颌骨采用游离髂嵴移植,采用覆盖/嵌入或置入式移植技术进行重建。上颌骨吸收模式的终点决定了所使用的移植技术。骨移植愈合6个月后植入骨内种植体。使用RFA对种植体稳定性进行4次测量:种植体植入时、愈合6至8个月后、桥体加载6个月和3年后。在拆除上部结构(Procera种植体桥,诺贝尔生物保健公司,瑞典哥德堡)后的两次后期RFA记录时进行个体检查。每年对边缘骨水平进行放射学随访。
25例患者完成随访。共植入192颗种植体,3年随访时生存率为90%。女性以及重建前吸收程度为6级的种植体位置是种植体失败风险显著增加的因素(多因素逻辑回归)。20颗失败种植体中有12颗在加载前丢失(早期失败)。基线(桥体交付)至3年随访期间,边缘骨水平变化为0.3±0.3mm。所有种植体的种植体稳定性商(ISQ)值在基台连接时(60.2±7.3)与桥体加载6个月后(62.5±5.5)有显著差异(配对数据的Wilcoxon符号秩检验,p = 0.05),但在桥体加载6个月和3年后(61.8±5.5)无显著差异。比较种植体植入时单个种植体的ISQ值,成功和失败种植体之间存在显著差异(Mann-Whitney U检验,p = 0.004)。在3年随访时,所有25例患者均安装了固定种植体桥。
这项使用放射学检查和RFA测量的临床随访表明,对于采用自体骨重建且延迟植入骨内种植体的萎缩无牙上颌骨患者,可获得可预测且稳定的长期结果。植入时的ISQ值可能可作为种植体失败风险水平的指标。