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对应用于充血性心力衰竭患者的无创双水平压力机械通气所导致的通气和血流动力学变化的分析。

Analysis of ventilation and hemodynamic changes resulting from noninvasive bilevel pressure mechanical ventilation applied to patients with congestive heart failure.

作者信息

de Barros Ariadne Fernandes, de Barros Luciana Costa, Sangean Márcia Cristina, Vega Joaquim Minuzo

机构信息

Hospital Estadual Mario Covas, Santo André, SP, Brazil.

出版信息

Arq Bras Cardiol. 2007 Jan;88(1):96-103. doi: 10.1590/s0066-782x2007000100016.

Abstract

OBJECTIVE

To observe in practice how noninvasive bilevel positive pressure, applied at different levels, may interfere with systolic arterial pressure (SAP), diastolic arterial pressure (DAP), mean arterial pressure (MAP), heart rate (HR), respiratory rate (RR), and peripheral oxygen saturation (SpO2), in patients with congestive heart failure (CHF).

METHODS

Fourteen CHF patients (mean age 62.85 years) were treated with noninvasive bilevel mechanical ventilation. Patients were consecutively treated with an expiratory positive airway pressure (EPAP) of 5 cmH2O, 10 cmH2O, 15 cmH2O, 10 cmH2O, and 5 cmH2O, maintaining a variation in pressure (deltaP) of 5 cmH2O between the inspiratory pressure (IPAP) and the expiratory pressure (EPAP). Ventilation and hemodynamic data were collected at these time points, as well as 5 minutes before the beginning of the protocol and 5 minutes after its completion.

RESULTS

A statistically significant difference was observed in the respiratory rate between the moment just before the beginning of the protocol and 5 minutes after positive pressure mask placement (p=0.022), and in oxygen saturation, between the final minute of EPAP at 5 cmH2O and after the removal of the mask (p=0.05).

CONCLUSION

Noninvasive bilevel mechanical ventilation improves oxygenation and reduces respiratory work, thus being beneficial for patients with congestive heart failure. It was not possible to observe statistically significant changes in the hemodynamic data due to the small number of patients and to other associated heart diseases.

摘要

目的

在实践中观察不同水平的无创双水平正压通气对充血性心力衰竭(CHF)患者的收缩压(SAP)、舒张压(DAP)、平均动脉压(MAP)、心率(HR)、呼吸频率(RR)和外周血氧饱和度(SpO2)的影响。

方法

14例CHF患者(平均年龄62.85岁)接受无创双水平机械通气治疗。患者依次接受5 cmH2O、10 cmH2O、15 cmH2O、10 cmH2O和5 cmH2O的呼气末正压(EPAP)治疗,吸气压力(IPAP)和呼气压力(EPAP)之间保持5 cmH2O的压力变化(ΔP)。在这些时间点以及方案开始前5分钟和结束后5分钟收集通气和血流动力学数据。

结果

在方案开始前的时刻与正压面罩放置后5分钟之间的呼吸频率(p = 0.022),以及在5 cmH2O的EPAP最后一分钟与面罩移除后之间的血氧饱和度(p = 0.05),观察到有统计学意义的差异。

结论

无创双水平机械通气可改善氧合并减少呼吸功,因此对充血性心力衰竭患者有益。由于患者数量少以及其他相关心脏病,无法观察到血流动力学数据有统计学意义的变化。

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