Tsunoda Koichi, Ishimoto Shin-Ichi, Suzuki Mitsuya, Hara Makoto, Yamaguchi Hiroya, Sugimoto Masahiro, Takeuchi Satoshi, Nito Takaharu, Higo Ryuzaburo, Saigusa Hideto, Tsunoda Atsunobu, Tayama Niro
Department of Artificial Organs and Otolaryngology, National Institute of Sensory Organs, Tokyo, Japan.
Acta Otolaryngol. 2007 Jan;127(1):88-92. doi: 10.1080/00016480600606665.
According to our previous study, lifestyle modification in combination with drug therapy is much more effective than drug therapy alone in cases of laryngopharyngeal reflux (LPR). Most patients with LPR will have chronic gastro-esophageal reflux diseases (GERD) and require long-term medical therapy for control, resulting in high total expenditure on pharmacologic agents. We combined pharmacologic management with lifestyle modifications for the management of GERD with successful outcomes in patients with GERD-related laryngeal granulomas. Although further studies are needed, guidance concerning lifestyle modifications in combination with PPI therapy may be not only a clinically effective but also a cost-effective method for the management of laryngeal granulomas caused by gastro-esophageal reflux.
