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嗅觉障碍患者的临床经验及其生活质量。

Clinical experience with patients with olfactory complaints, and their quality of life.

作者信息

Brämerson Annika, Nordin Steven, Bende Mats

机构信息

Department of Otorhinolaryngology, Central Hospital, Skövde, Sweden.

出版信息

Acta Otolaryngol. 2007 Feb;127(2):167-74. doi: 10.1080/00016480600801357.

DOI:10.1080/00016480600801357
PMID:17364348
Abstract

CONCLUSION

A special consulting team for patients with olfactory disorders would be able to verify, describe, and explain the characteristics of the disorders, also in cases where a patient experiences a disorder, but has a normal sense of smell.

OBJECTIVES

The general purpose of this paper was to present our experience with patients seeking medical attention for olfactory disorders, and to describe how quantitative and qualitative olfactory disorders are diagnosed, what the etiologies are, and how quality of life is compromised in patients with olfactory disorders.

SUBJECTS AND METHODS

This investigation was performed prospectively over a 10-year period by one physician responsible for the consulting team for patients with olfactory disorders. Based on a standardized clinical examination, a structured interview, and assessment of olfactory function, its aim was to diagnose quantitative and qualitative disorders in 303 consecutive patients. Health-related quality of life was assessed with the Nottingham Health Profile (NHP) in about one-third of patients.

RESULTS

In the majority of patients, a reduced sense of smell was found after testing. Often, but not always, this was combined with qualitative disorders. Dominating etiologies were infections, nasal polyposis, head trauma, and aging. Patients complaining of olfactory disorders experience a significantly reduced quality of life regarding the impact of their health problem on paid employment, household work, and social and family life.

摘要

结论

一个针对嗅觉障碍患者的特殊咨询团队能够核实、描述并解释这些障碍的特征,即便在患者虽患有嗅觉障碍但嗅觉正常的情况下亦是如此。

目的

本文的总体目的是介绍我们在为嗅觉障碍患者提供医疗服务方面的经验,并描述如何诊断定量和定性嗅觉障碍、其病因是什么,以及嗅觉障碍患者的生活质量是如何受到影响的。

对象与方法

本研究由负责嗅觉障碍患者咨询团队的一名医生在10年期间前瞻性地进行。基于标准化临床检查、结构化访谈和嗅觉功能评估,其目的是对303例连续患者的定量和定性障碍进行诊断。约三分之一的患者使用诺丁汉健康量表(NHP)评估与健康相关的生活质量。

结果

在大多数患者中,测试后发现嗅觉减退。通常,但并非总是如此,这与定性障碍同时存在。主要病因是感染、鼻息肉、头部外伤和衰老。抱怨嗅觉障碍的患者在健康问题对有偿工作、家务劳动以及社交和家庭生活的影响方面,生活质量显著下降。

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