Lin I-Hung, Hwang Chung-Feng, Huang Hsiu-Yu, Chien Chih-Yen
Department of Otolaryngology, Chang Gung Memorial Hospital - Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Acta Otolaryngol. 2007 Feb;127(2):206-8. doi: 10.1080/00016480500401027.
Small cell carcinoma is predominantly found in the lung and only about 5% of small cell carcinoma cases have been noted to be extrapulmonary; these are commonly found in the esophagus, pancreas, skin, uterus, and breast. A head and neck origin for small cell carcinoma is extremely rare. Both pulmonary and extrapulmonary small cell carcinomas usually have a good response to chemotherapy initially, but a poor prognosis finally. We report here a case of small cell carcinoma of the nasopharynx. The patient underwent chemotherapy and irradiation for the disease, but died of lung metastasis 38 months later.
小细胞癌主要发生于肺，仅有约5%的小细胞癌病例被发现为肺外病变；这些病例常见于食管、胰腺、皮肤、子宫和乳腺。小细胞癌起源于头颈部极为罕见。肺内和肺外小细胞癌通常最初对化疗反应良好，但最终预后较差。我们在此报告一例鼻咽癌。该患者因该病接受了化疗和放疗，但38个月后死于肺转移。
