Becker D, Orr A, Weizman A, Kotler M, Pines A
Ness Ziona-Beer Ya'acov Mental Health Center, Research Unit, Internal Medicine Department T, Sackler School of Medicine, Tel Aviv University, Israel.
Climacteric. 2007 Feb;10(1):46-50. doi: 10.1080/13697130601174374.
Depressive symptoms are frequent through the different stages of a woman's reproductive cycle. The aim of this study was to evaluate a possible correlation of depressive mood before menstruation, during pregnancy, after delivery and around the menopause.
The sample consisted of 110 women (mean age 52 years, standard deviation 4 years) who rated their mood at present and retrospectively at different stages of the reproductive cycle. Mood was rated using a visual analogue scale.
A significant statistical association was found between the present mood and mood at the premenstrual period, but not with mood at pregnancy or after delivery. These findings were independent of age, menopausal status or use of hormone replacement therapy.
The statistical association between depressed mood around menopause and before menstruation supports the assumption that there is a common etiology, which could be attributed to hormonal or psychological factors, or both.
抑郁症状在女性生殖周期的不同阶段很常见。本研究的目的是评估月经前、孕期、产后及绝经前后抑郁情绪之间可能存在的相关性。
样本包括110名女性（平均年龄52岁，标准差4岁），她们对自己当前的情绪以及回顾性地对生殖周期不同阶段的情绪进行评分。情绪评分采用视觉模拟量表。
发现当前情绪与经前期情绪之间存在显著的统计学关联，但与孕期或产后情绪无关。这些发现不受年龄、绝经状态或激素替代疗法使用情况的影响。
绝经前后抑郁情绪与月经前抑郁情绪之间的统计学关联支持了存在共同病因的假设，这可能归因于激素或心理因素，或两者皆有。
