Woods N Fugate, Mariella A, Mitchell E Sullivan
University of Washington, School of Nursing, Seattle, Washington 98195-7260, USA.
Climacteric. 2006 Jun;9(3):195-203. doi: 10.1080/13697130600730663.
To describe patterns of depressed mood during the menopausal transition (MT) and to investigate relationships between patterns of depressed mood and MT stages.
Women during MT and early postmenopause rated depressed mood from 0 to 4 in a 3-day diary. Variables were percentage days with zero ratings, days with ratings of 3 or 4, and slope of ratings over time. Cluster analysis was used.
Six distinct clusters were identified for 164 women. The three largest clusters (n = 134) had depressed mood ratings of zero (93% of days, 73%, 50%, respectively). Ratings of 3 or 4 were infrequent for these three clusters (0%, 3%, 9%, respectively). The three smallest clusters (n = 30) had zero ratings for 32% of days, 14% and 8%, respectively. The fourth cluster had 16% rated 3 or 4 with a positive slope. The fifth and sixth clusters had 23% and 6% of days at 3 or 4 with a negative slope. MT stage was not related to depressed mood ratings. Most women did not have depressed mood during the MT. Of those who did, some experienced improvement.
The majority of women for the majority of the time experienced MT without a high severity of depressed mood while a small group of women had mood worsening over time and others improved. Depressed mood that occurs during the MT should not be attributed automatically to menstrual cycle changes or normative changes. Instead, features of a woman's life that contribute to depression should also be considered.
描述围绝经期过渡（MT）期间的抑郁情绪模式，并研究抑郁情绪模式与MT阶段之间的关系。
处于MT和绝经后早期的女性在一份为期3天的日记中对抑郁情绪进行0至4分的评分。变量包括评分为零的天数百分比、评分为3或4的天数以及评分随时间的斜率。采用聚类分析。
对164名女性识别出六个不同的聚类。三个最大的聚类（n = 134）的抑郁情绪评分为零（分别为93%的天数、73%、50%）。这三个聚类中评分为3或4的情况很少见（分别为0%、3%、9%）。三个最小的聚类（n = 30）评分为零的天数分别为32%、14%和8%。第四个聚类有16%的评分为3或4且斜率为正。第五和第六个聚类有23%和6%的天数评分为3或4且斜率为负。MT阶段与抑郁情绪评分无关。大多数女性在MT期间没有抑郁情绪。有抑郁情绪的女性中，一些人症状有所改善。
大多数女性在大多数时间经历MT时抑郁情绪严重程度不高，而一小部分女性情绪随时间恶化，其他女性则有所改善。MT期间出现的抑郁情绪不应自动归因于月经周期变化或正常变化。相反，还应考虑导致女性抑郁的生活特征。
