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通过食用以乳制品副产品喂养的猪所产猪肉,模拟人类对苄青霉素残留的暴露情况。

Simulation of human exposure to benzylpenicillin residues via pork originating from pigs fed with a dairy by-product.

作者信息

Karlström U, Nuotio L, Lindfors E, Maijala R

机构信息

EVIRA-Department of Risk Assessment, Finnish Food Safety Authority, Mustialankatu 3, Fl-00790, Helsinki, Finland.

出版信息

Food Addit Contam. 2007 Mar;24(3):266-73. doi: 10.1080/02652030601039005.

DOI:10.1080/02652030601039005
PMID:17364928
Abstract

The use of food industry by-products for feeding is restricted by European Union by-product regulation (1774/2002). However, the actual public health risks involved in the use of such products are poorly recognized. This study focuses on bovine milk rejected at the dairy because of a positive result in antimicrobial drug testing and thereafter used as feed for finisher pigs in Finland. In theory, this current practice could expose pork consumers to antimicrobial drug residues. Raw bulk milk samples originating from rejected lots were analysed with a multiresidue method detecting five beta-lactams, including benzylpenicillin. Based on the probabilistic simulation model developed, concentrations of benzylpenicillin in pork invariably remained below 1% of the maximum residue limit. Therefore, the use of this by-product as feed with the current practice was considered to pose only a negligible risk to consumers of pork products.

摘要

欧盟副产品法规(1774/2002)限制了食品工业副产品用于喂养的用途。然而,人们对使用此类产品所涉及的实际公共卫生风险认识不足。本研究聚焦于因抗菌药物检测呈阳性而在乳品厂被拒收的牛乳,这些牛乳随后在芬兰被用作育肥猪的饲料。从理论上讲,当前这种做法可能会使猪肉消费者接触到抗菌药物残留。采用多残留方法对来自被拒收批次的生散装牛奶样本进行分析,该方法可检测包括苄青霉素在内的五种β-内酰胺类药物。基于所开发的概率模拟模型,猪肉中苄青霉素的浓度始终低于最大残留限量的1%。因此,按照当前做法将这种副产品用作饲料被认为对猪肉产品消费者仅构成可忽略不计的风险。

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