一种来自菊蒿叶菊蒿的新型吉马烷型倍半萜内酯。

A new germacranolide-type sesquiterpene lactone from Tanacetum santolinoides.

作者信息

Mahmoud Ahmed A, Al-Omair Mohammed A, Iinuma Munekazu

机构信息

Department of Chemistry, College of Science, King Faisal University, Hofuf, Saudi Arabia. aahmed@@kfu.edu.sa

出版信息

Nat Prod Res. 2007 Feb;21(2):156-60. doi: 10.1080/14786410601129820.

DOI:10.1080/14786410601129820

PMID:17365703

Abstract

A new germacranolide-type sesquiterpene lactone, 1alpha-hydroxy-3-oxo-7alpha,11betaH-germacra-4Z,9Z-dien-12,6alpha-olide (1), was isolated from the CH2Cl2--MeOH extract of the aerial parts of Tanacetum santolinoides. Its structure was determined by spectroscopic techniques including, IR, high-resolution-EIMS, and extensive 400 MHz one- and two-dimensional NMR-analysis (1H, 13C-NMR, DEPT, 1H--1H COSY, HMQC, HMBC, and NOE experiments).

摘要

从菊蒿叶菊（Tanacetum santolinoides）地上部分的二氯甲烷 - 甲醇提取物中分离出一种新的吉马烷型倍半萜内酯，1α - 羟基 - 3 - 氧代 - 7α,11βH - 吉马 - 4Z,9Z - 二烯 - 12,6α - 内酯（1）。其结构通过光谱技术确定，包括红外光谱（IR）、高分辨率电子轰击质谱（high - resolution - EIMS）以及广泛的400 MHz一维和二维核磁共振分析（1H、13C - NMR、DEPT、1H - 1H COSY、HMQC、HMBC和NOE实验）。