一名年轻、免疫功能正常的患者出现不寻常的水痘带状疱疹病毒再激活，伴有脑膜脑炎，随后发生横纹肌溶解和肾衰竭。

Unusual onset of varicella zoster reactivation with meningoencephalitis, followed by rhabdomyolysis and renal failure in a young, immunocompetent patient.

作者信息

Pirounaki Maria, Liatsos George, Elefsiniotis Ioannis, Skounakis Michail, Moulakakis Antonios

机构信息

Department of Internal Medicine, Hippokration General Hospital., Athens, Vasilissis Sofias 114, Greece.

出版信息

Scand J Infect Dis. 2007;39(1):90-3. doi: 10.1080/00365540600798809.

DOI:10.1080/00365540600798809

PMID:17366023

Abstract

We present an unusual onset of meningoencephalitis due to VZV reactivation, with increased intrathecal production of IgG VZV antibodies and negative PCR, in a young, immunocompetent adult. Herpes zoster erupted 5 d later. Rare complication of VZV-related rhabdomyolysis occurred, with subsequent ARF, in combination with acyclovir and ceftriaxone. The patient recovered fully and remained healthy.

摘要

我们报告了一例因水痘-带状疱疹病毒（VZV）再激活导致的脑膜脑炎不寻常发病情况，该患者为一名年轻的免疫功能正常成年人，其鞘内IgG VZV抗体产生增加而PCR检测为阴性。5天后出现带状疱疹。发生了VZV相关横纹肌溶解的罕见并发症，随后出现急性肾衰竭，同时使用了阿昔洛韦和头孢曲松。患者完全康复且保持健康。