Rouleau Jacinthe, Longmuir Reid, Lee Andrew G
The University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Semin Ophthalmol. 2007 Jan-Mar;22(1):25-8. doi: 10.1080/08820530601162891.
To report a case of optic disc edema with adjacent retinal ischemia in ulcerative colitis.
Photo essay.
A 36-year-old white man presented with visual loss OD. Past medical history was significant for ulcerative colitis. The patient had suffered presumed non-arteritic anterior ischemic optic neuropathy OS one year prior to the episode OD. Ophthalmoscopic exam showed optic disc edema associated with an area of adjacent retinal ischemia that was confirmed on fluorescein angiography OD. An extensive evaluation for infectious, inflammatory, vasculitic, and hypercoagulable etiologies was negative. The presumptive diagnosis of ulcerative colitis-related ischemic optic neuropathy with simultaneous retinal ischemia was made. The patient was treated with antiplatelet therapy and the vision stabilized but did not recover.
To our knowledge, this is the first report in the English language literature of a simultaneous ischemic event involving the optic nerve and the adjacent retina in a patient with ulcerative colitis.
报告一例溃疡性结肠炎伴视神经盘水肿及相邻视网膜缺血的病例。
图片报道。
一名36岁白人男性,右眼视力丧失。既往病史有溃疡性结肠炎。该患者在右眼发病前一年曾患疑似非动脉炎性前部缺血性视神经病变累及左眼。眼底检查显示视神经盘水肿,伴有相邻视网膜缺血区,右眼荧光素血管造影证实了这一点。对感染、炎症、血管炎和高凝病因进行的广泛评估均为阴性。作出了溃疡性结肠炎相关缺血性视神经病变伴同时性视网膜缺血的初步诊断。患者接受了抗血小板治疗,视力稳定但未恢复。
据我们所知,这是英文文献中首例关于溃疡性结肠炎患者同时发生涉及视神经和相邻视网膜的缺血性事件的报告。