产前暴露于可卡因的9岁儿童的母亲抑郁及认知特征

Maternal depression and cognitive features of 9-year-old children prenatally-exposed to cocaine.

作者信息

Marques Paul R, Pokorni Judith L, Long Toby, Teti Laureen O

机构信息

Pacific Institute for Research and Evaluation, Calverton, Maryland 20705, USA.

出版信息

Am J Drug Alcohol Abuse. 2007;33(1):45-61. doi: 10.1080/00952990601082647.

DOI:10.1080/00952990601082647

PMID:17366245

Abstract

This study evaluated cocaine exposure and maternal characteristics as competing predictors of school-age cognitive, achievement, and language performance. One group of 47 exposed 9-year-old children were first studied in an earlier prenatal study. A non-exposed contrast group (n = 46) served as a reference. Maternal measures included: IQ, psychopathology, drugs, demographics, and environment. Child intelligence, language, and achievement scores were inversely related to maternal IQ and depression scores, with cocaine exposure significant secondary or tertiary predictors for many children. Verbal IQ scores of exposed children strongly reflected maternal depression (r = .54) but no such relationship was found among the non-exposed cohort (r = .00).

摘要

本研究评估了可卡因暴露和母亲特征作为学龄儿童认知、学业成绩及语言表现的竞争预测因素。一组47名暴露于可卡因的9岁儿童在早期的产前研究中首次接受研究。一个未暴露的对照组（n = 46）作为参照。母亲的测量指标包括：智商、精神病理学、药物使用情况、人口统计学特征及环境。儿童的智力、语言及学业成绩得分与母亲的智商及抑郁得分呈负相关，对于许多儿童而言，可卡因暴露是显著的次要或第三预测因素。暴露儿童的言语智商得分强烈反映了母亲的抑郁（r = 0.54），但在未暴露队列中未发现此类关系（r = 0.00）。