一种用于通过SHAPE化学精确分析RNA二级和三级结构的快速作用试剂。 - Suppr

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A fast-acting reagent for accurate analysis of RNA secondary and tertiary structure by SHAPE chemistry.

作者信息

Mortimer Stefanie A, Weeks Kevin M

机构信息

Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599-3290, USA.

出版信息

J Am Chem Soc. 2007 Apr 11;129(14):4144-5. doi: 10.1021/ja0704028. Epub 2007 Mar 17.

DOI:10.1021/ja0704028

PMID:17367143

Abstract

摘要

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A fast-acting reagent for accurate analysis of RNA secondary and tertiary structure by SHAPE chemistry.

作者信息

Mortimer Stefanie A, Weeks Kevin M

机构信息

Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599-3290, USA.

出版信息

J Am Chem Soc. 2007 Apr 11;129(14):4144-5. doi: 10.1021/ja0704028. Epub 2007 Mar 17.

DOI:10.1021/ja0704028

PMID:17367143

Abstract

摘要

相似文献

A fast-acting reagent for accurate analysis of RNA secondary and tertiary structure by SHAPE chemistry.

J Am Chem Soc. 2007 Apr 11;129(14):4144-5. doi: 10.1021/ja0704028. Epub 2007 Mar 17.

RNA SHAPE chemistry reveals nonhierarchical interactions dominate equilibrium structural transitions in tRNA(Asp) transcripts.

J Am Chem Soc. 2005 Apr 6;127(13):4659-67. doi: 10.1021/ja0436749.

Selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE): quantitative RNA structure analysis at single nucleotide resolution.

Nat Protoc. 2006;1(3):1610-6. doi: 10.1038/nprot.2006.249.

Time-resolved RNA SHAPE chemistry.

J Am Chem Soc. 2008 Dec 3;130(48):16178-80. doi: 10.1021/ja8061216.

RNA SHAPE chemistry with aromatic acylating reagents.

Bioorg Med Chem Lett. 2015 Feb 1;25(3):566-70. doi: 10.1016/j.bmcl.2014.12.020. Epub 2014 Dec 15.

Determination of RNA tertiary structure by electron paramagnetic resonance spectroscopy (EPR).

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1661-4. doi: 10.1081/NCN-120023107.

Neutral networks of sequence to shape maps.

J Theor Biol. 2008 Feb 7;250(3):484-97. doi: 10.1016/j.jtbi.2007.09.012. Epub 2007 Sep 15.

SHAPE Selection (SHAPES) enrich for RNA structure signal in SHAPE sequencing-based probing data.

RNA. 2015 May;21(5):1042-52. doi: 10.1261/rna.047068.114. Epub 2015 Mar 24.

RNA structure analysis at single nucleotide resolution by selective 2'-hydroxyl acylation and primer extension (SHAPE).

J Am Chem Soc. 2005 Mar 30;127(12):4223-31. doi: 10.1021/ja043822v.

Diverse Reagent Scaffolds Provide Differential Selectivity of 2'-OH Acylation in RNA.

J Am Chem Soc. 2023 Jan 11;145(1):143-151. doi: 10.1021/jacs.2c09040. Epub 2022 Dec 21.

引用本文的文献

Sequence, structure, and affinity of miR-34a binding sites determine repression efficacy.

Nucleic Acids Res. 2025 Jul 8;53(13). doi: 10.1093/nar/gkaf633.

Improving RNA Secondary Structure Prediction Through Expanded Training Data.

bioRxiv. 2025 May 3:2025.05.03.652028. doi: 10.1101/2025.05.03.652028.

A cohort of mRNAs undergo high-stoichiometry NSUN6-mediated site-specific mC modification.

Nat Commun. 2025 Jul 4;16(1):6119. doi: 10.1038/s41467-025-60873-4.

Transcriptome-wide RNA accessibility mapping reveals structured RNA elements and pervasive conformational rearrangements under stress.

bioRxiv. 2025 Jun 5:2025.06.05.658101. doi: 10.1101/2025.06.05.658101.

The macrophage-intrinsic MDA5/IRF5 axis drives HIV-1 intron-containing RNA-induced inflammatory responses.

J Clin Invest. 2025 Jun 10;135(16). doi: 10.1172/JCI187663. eCollection 2025 Aug 15.

RNA Binding to CCRRM of PABPN1 Induces Conformation Change.

Biology (Basel). 2025 Apr 17;14(4):432. doi: 10.3390/biology14040432.

Investigating the interplay between RNA structural dynamics and RNA chemical probing experiments.

Nucleic Acids Res. 2025 Apr 10;53(7). doi: 10.1093/nar/gkaf290.

The LSmAD Domain of Ataxin-2 Modulates the Structure and RNA Binding of Its Preceding LSm Domain.

Cells. 2025 Mar 6;14(5):383. doi: 10.3390/cells14050383.

Chemotranscriptomic profiling with a thiamine monophosphate photoaffinity probe.

Chem Sci. 2025 Feb 11;16(11):4725-4731. doi: 10.1039/d4sc06189f. eCollection 2025 Mar 12.

Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-Viral hsa-miR-132 Processing in CEM-SS Cells.

Noncoding RNA. 2025 Jan 20;11(1):8. doi: 10.3390/ncrna11010008.