Rasi Abbas, Tajziehchi Leila, Shaianfar Nasrin
Department of Dermatology, Iran University of Medical Sciences, Tehran, Iran.
Arch Iran Med. 2007 Apr;10(2):250-2.
Distant metastases are unusual at presentation and during the course of ovarian carcinoma. Skin metastases may be the first presenting sign of metastatic carcinoma of the ovary. Ovarian epithelial adenocarcinoma rarely metastasizes to the skin, and can be seen in less than 4% of patients. It usually presents as subcutaneous nodules and, less commonly, as inflammatory metastases, which mimic viral or bacterial skin infections. The histology in most of the tumors is serous papillary adenocarcinoma (grade 1 or 2). The prognosis in most patients is poor, thus palliative treatment is usually indicated. We report a patient with widespread skin metastases and review the literature on this rare presentation.
远处转移在卵巢癌就诊时及病程中并不常见。皮肤转移可能是卵巢转移性癌的首个表现体征。卵巢上皮腺癌很少转移至皮肤，在不到4%的患者中可见。其通常表现为皮下结节，较少见的表现为炎症性转移，类似病毒或细菌性皮肤感染。大多数肿瘤的组织学类型为浆液性乳头状腺癌（1级或2级）。大多数患者预后较差，因此通常需要进行姑息治疗。我们报告1例有广泛皮肤转移的患者，并回顾关于这种罕见表现的文献。
