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德国儿童糖尿病患者住院风险中持续存在的社会差异——来自1277名糖尿病儿童和青少年的前瞻性数据。

Persistent social disparities in the risk of hospital admission of paediatric diabetic patients in Germany-prospective data from 1277 diabetic children and adolescents.

作者信息

Icks A, Rosenbauer J, Strassburger K, Grabert M, Giani G, Holl R W

机构信息

Institute for Biometrics and Epidemiology, German Diabetes Center at Heinrich-Heine-University Düsseldorf, Germany.

出版信息

Diabet Med. 2007 Apr;24(4):440-2. doi: 10.1111/j.1464-5491.2007.02105.x. Epub 2007 Mar 15.

Abstract

BACKGROUND

Reduction of social inequality in health care is a major target in many countries. The risk of hospital admission is thought to be higher in diabetic children from socially deprived families but actual data are lacking.

METHODS

Based on a nationwide prospective computer-based documentation program (DPV), we determined the association between three social parameters (parental professional education, one-parent family vs. complete family, migration background) and the risk for post-onset hospital admission, as well as the number of hospital admission days in children and adolescents < 20 years of age with diabetes onset in 2002-2005 [n = 1277, 56% male, mean age at onset 8.5 (4.1) years]. We estimated relative risks with 95% confidence intervals, adjusting for age, sex, and diabetes centre (cluster), using random effect models.

RESULTS

Forty-two per cent of the study subjects were admitted to hospital at least once during follow-up. The incidence of hospital admissions was 0.46 (0.43-0.49) per person year, and there were 2.72 (2.65-2.80) hospital days per person year. Hospital admissions and hospital days were higher in girls than in boys (significant for hospital days, P < 0.05), and significantly lower in adolescents aged 15-19 compared with children aged 0-4 years (P < 0.05 in all models). Hospital admission rates were significantly higher in children from lower-educated parents, single-parent families, and families with a migration background (all P < 0.05).

DISCUSSION

We found post-onset hospital admission rates to be higher in diabetic children and adolescents from socially deprived families. In comparison with an analysis in the 1990s, no decrease in social disparity in hospital admission risk was found.

摘要

背景

减少医疗保健方面的社会不平等是许多国家的主要目标。人们认为,来自社会贫困家庭的糖尿病儿童住院风险更高,但缺乏实际数据。

方法

基于一项全国性的前瞻性计算机文档程序(DPV),我们确定了三个社会参数(父母职业教育程度、单亲家庭与完整家庭、移民背景)与发病后住院风险之间的关联,以及2002 - 2005年发病的20岁以下糖尿病儿童和青少年的住院天数[n = 1277,男性占56%,发病时平均年龄8.5(4.1)岁]。我们使用随机效应模型,在调整年龄、性别和糖尿病中心(聚类)后,估计了95%置信区间的相对风险。

结果

42%的研究对象在随访期间至少住院一次。住院发生率为每人每年0.46(0.43 - 0.49)次,每人每年住院天数为2.72(2.65 - 2.80)天。女孩的住院次数和住院天数高于男孩(住院天数差异显著,P < 0.05),15 - 19岁青少年的住院次数和住院天数显著低于0 - 4岁儿童(所有模型中P < 0.05)。父母受教育程度较低、单亲家庭和有移民背景家庭的儿童住院率显著更高(所有P < 0.05)。

讨论

我们发现,来自社会贫困家庭的糖尿病儿童和青少年发病后的住院率更高。与20世纪90年代的分析相比,住院风险的社会差距没有缩小。

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