Takanashi Jun-ichi, Tada Hiroko, Fujii Katsunori, Barkovich A James
Department of Pediatrics, Kameda Medical Center, 929 Higashi-cho, Kamogawa-shi, Chiba 296-8602, Japan.
Brain Dev. 2007 Sep;29(8):522-4. doi: 10.1016/j.braindev.2007.02.001. Epub 2007 Mar 23.
MR imaging of a patient with epilepsy and psychomotor retardation at 5 months revealed parieto-occipital pachygyria with almost normal cortical appearance and thickness in the frontal region; this appearance evolved into diffuse pachygyria at 7 years. The change of the MR imaging findings may have resulted from myelination in the intracortical and subcortical fibers. It is important for clinicians to be aware of the longitudinal changes of the cerebral cortex in lissencephaly.
一名患有癫痫和精神运动发育迟缓的患者在5个月时的磁共振成像显示顶枕叶巨脑回,额叶皮质外观和厚度几乎正常;这种表现到7岁时演变为弥漫性巨脑回。磁共振成像结果的变化可能是由于皮质内和皮质下纤维的髓鞘形成。临床医生了解无脑回畸形中大脑皮质的纵向变化很重要。