Smith Jack B, Loushine Robert J, Weller R Norman, Rueggeberg Frederick A, Whitford Gary M, Pashley David H, Tay Franklin R
Department of Endodontics, School of Dentistry, Medical College of Georgia, Augusta, GA 30912, USA.
J Endod. 2007 Apr;33(4):463-7. doi: 10.1016/j.joen.2006.12.002. Epub 2007 Feb 20.
This study examined the effects of calcium-depleting endodontic irrigants, ethylenediamine tetra-acetic acid (EDTA) and BioPure MTAD, on the dissolution, surface characteristics, and ultrastructural characteristics of white mineral trioxide aggregate (MTA). The latter was mixed in a 0.35 water-cement ratio, condensed into cylindrical wells created in Plexiglas platforms, and allowed to harden completely before initial treatment with 1.3% NaOCl and final treatments with either 17% EDTA for 5 minutes, or BioPure MTAD for 1, 3, or 5 minutes. Analysis of the mean depths of material removed using three-dimensional profilometry revealed significantly more material removed by BioPure MTAD. Although these minor depth changes (<10 microm) are unlikely to cause clinical concern, the BioPure MTAD-treated MTA surfaces exhibited higher surface roughness and with more calcium extracted when compared with EDTA treatment. Decomposition of particle-binding hydration phases by acid corrosion raises potential concern on the strength and sealing properties of MTA-repaired perforations following final irrigation by BioPure MTAD.
