Abarca V Katia
Departamento de Pediatría, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Rev Chilena Infectol. 2007 Feb;24(1):53-6. doi: 10.4067/s0716-10182007000100008. Epub 2007 Mar 8.
The objective of the surveillance systems of vaccine adverse events is monitoring events temporally related to vaccination, to evaluate their causality with the vaccine and to detect events after the introduction of new vaccines. The ultimate goal of these systems is to provide the population with the best safety standard of the vaccines. The surveillance system can be passive (spontaneous reports) or active (active follow up of vaccinees); the majority of them are passive. The article gives a brief review of the most known vaccine adverse events surveillance systems, including the American Vaccine Adverse Events Report System (VAERS), the Canadian and European systems, a commentary about the Chilean one, highlighting its main advantages and also its limitations.
疫苗不良事件监测系统的目标是监测与疫苗接种在时间上相关的事件，评估这些事件与疫苗的因果关系，并在新疫苗引入后检测相关事件。这些系统的最终目标是为民众提供疫苗的最佳安全标准。监测系统可以是被动的（自发报告）或主动的（对疫苗接种者进行主动随访）；其中大多数是被动的。本文简要回顾了最知名的疫苗不良事件监测系统，包括美国疫苗不良事件报告系统（VAERS）、加拿大和欧洲的系统，并对智利的系统进行了评论，突出了其主要优点和局限性。
