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一种新的实验模型:大鼠背侧(胁腹和髋部)带血管蒂皮瓣

A new experimental model: the vascular pedicle cutaneous flap over the dorsal aspect (flank and hip) of the rat.

作者信息

Syed S A, Tasaki Y, Fujii T, Hirano A, Kobayashi K

机构信息

Department of Plastic and Reconstructive Surgery, Nagasaki University School of Medicine, Japan.

出版信息

Br J Plast Surg. 1992 Jan;45(1):23-5. doi: 10.1016/0007-1226(92)90109-b.

DOI:10.1016/0007-1226(92)90109-b
PMID:1737202
Abstract

Cutaneous vascular anatomy of the flank and the hip was studied in the rat. Investigation was done by anatomical dissection, ink injection to the axial artery and flap harvesting in living rats. Anatomical dissection and India ink injection revealed that the rat's flank and hip skin derives its blood supply from the iliac branch of the iliolumbar artery, which originates from the lateral aspect of the abdominal aorta. The vascular territory of the iliac branch of the iliolumbar artery was defined as follows: the medial border--along the midline of the back from the 12th rib to the proximal part of the tail; the lateral border-anterior axillary line corresponding with the length of the medial border; the cephalic border--a line joining the medial and lateral border at the level of the 12th rib; and the caudal border--the posterior lateral line of the hip. On the basis of the vascular territory demarcated by India ink injection, bilateral vascular pedicle island cutaneous flaps were harvested in living rats. Results showed total survival of all flaps. This flap is easily made, and it could be used as a reliable model for flap research.

摘要

对大鼠的侧腹和臀部皮肤血管解剖结构进行了研究。通过解剖、向轴动脉注射墨水以及在活体大鼠身上切取皮瓣来开展研究。解剖和印度墨水注射显示,大鼠的侧腹和臀部皮肤的血液供应来自腰髂动脉的髂支,该动脉起源于腹主动脉的外侧。腰髂动脉髂支的血管分布区域定义如下:内侧边界——沿着背部中线,从第12肋至尾巴近端;外侧边界——与内侧边界长度相对应的腋前线;头侧边界——在第12肋水平连接内侧和外侧边界的线;尾侧边界——臀部的后外侧线。基于印度墨水注射划定的血管分布区域,在活体大鼠身上切取了双侧血管蒂岛状皮瓣。结果显示所有皮瓣均完全存活。这种皮瓣制作简便,可作为皮瓣研究的可靠模型。

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引用本文的文献

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Plast Reconstr Surg Glob Open. 2017 Sep 11;5(9):e1454. doi: 10.1097/GOX.0000000000001454. eCollection 2017 Sep.