Ruhl Constance E, Everhart James E
Social & Scientific Systems, Inc., Silver Spring, MD 20910, USA.
Am J Epidemiol. 2007 May 15;165(10):1154-61. doi: 10.1093/aje/kwm011. Epub 2007 Mar 20.
The authors examined risk factors for incident inguinal hernia among US adults (5,316 men and 8,136 women) participating in the First National Health and Nutrition Examination Survey (1971-1975) who were followed through 1992-1993 for a hospital (International Classification of Diseases, Ninth Revision, Clinical Modification, code 550) or physician diagnosis of inguinal hernia. Ninety-six percent of the baseline cohort was recontacted, with a median follow-up of 18.2 years (range, 0.02-22.1 years). Because the cumulative incidence of inguinal hernia was higher among men (13.9%) than among women (2.1%), more detailed analyses were conducted in men. Among men in multivariate analysis, a higher incidence (p < 0.05) of inguinal hernia was associated with an age of 40-59 years (hazard ratio (HR) = 2.2, 95% confidence interval (CI): 1.7, 2.8), an age of 60-74 years (HR = 2.8, 95% CI: 2.2, 3.6), and hiatal hernia (HR = 1.8, 95% CI: 1.2, 2.7), while Black race (HR = 0.58, 95% CI: 0.42, 0.79), being overweight (HR = 0.79, 95% CI: 0.66, 0.95), and obesity (HR = 0.51, 95% CI: 0.36, 0.71) were associated with a lower incidence. Among women, older age, rural residence, greater height, chronic cough, and umbilical hernia were associated with inguinal hernia. In the United States, inguinal hernias are common among men, especially with aging. The lower risk among heavier men was unexpected and bears further study.
作者研究了参与首次全国健康与营养检查调查(1971 - 1975年)的美国成年人(5316名男性和8136名女性)发生腹股沟疝的风险因素,这些人在1992 - 1993年期间接受随访,以确定是否有医院(国际疾病分类第九版临床修订本,代码550)诊断或医生诊断的腹股沟疝。对基线队列中的96%进行了再次联系,中位随访时间为18.2年(范围为0.02 - 22.1年)。由于男性腹股沟疝的累积发病率(13.9%)高于女性(2.1%),因此对男性进行了更详细的分析。在多变量分析中,男性腹股沟疝发病率较高(p < 0.05)与40 - 59岁年龄组(风险比(HR)= 2.2,95%置信区间(CI):1.7,2.8)、60 - 74岁年龄组(HR = 2.8,95% CI:2.2,3.6)以及食管裂孔疝(HR = 1.8,95% CI:1.2,2.7)相关,而黑人种族(HR = 0.58,95% CI:0.42,0.79)、超重(HR = 0.79,95% CI:0.66,0.95)和肥胖(HR = 0.51,95% CI:0.36,0.71)与较低发病率相关。在女性中,年龄较大、居住在农村、身高较高、慢性咳嗽和脐疝与腹股沟疝相关。在美国,腹股沟疝在男性中很常见,尤其是随着年龄增长。体重较重的男性风险较低这一情况出乎意料,值得进一步研究。