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异位妊娠的诊断与治疗史:一场医学冒险。

The history of the diagnosis and treatment of ectopic pregnancy: a medical adventure.

作者信息

Lurie S

机构信息

Department of Obstetrics and Gynecology, Kaplan Hospital, Rehovot, Israel.

出版信息

Eur J Obstet Gynecol Reprod Biol. 1992 Jan 9;43(1):1-7. doi: 10.1016/0028-2243(92)90235-q.

DOI:10.1016/0028-2243(92)90235-q
PMID:1737602
Abstract

From its indirect reference by Abulcasis (936-1013) and until the 19th century the ectopic pregnancy was known as a universally fatal accident. By reporting successful treatment of tubal pregnancy with salpingectomy in 1884 Robert Lawson Tait (1845-1899) started an era of almost 70 years of exclusively extirpative treatment of ectopic pregnancy. The technologic revolution of the 20th century improved diagnostic capabilities so that diagnosis of unruptured ectopic pregnancy becomes feasible and even mandatory. Side by side our understanding of the natural history of ectopic pregnancy improved. Many patients with early-resolving ectopic pregnancies escape surgical treatment. Preservation of future fertility became possible with the introduction of conservative surgical procedures and with the use of methotrexate. The main achievement in the treatment of ectopic pregnancy over the past 110 years is the dramatic decrease in mortality rate: from 72-90% in 1880 to 0.14% in 1990.

摘要

从阿布卡西(936 - 1013)对其间接提及,到19世纪,宫外孕一直被视为一种普遍致命的意外情况。1884年,罗伯特·劳森·泰特(1845 - 1899)报告了通过输卵管切除术成功治疗输卵管妊娠,由此开启了一个近70年的宫外孕单纯切除治疗时代。20世纪的技术革命提高了诊断能力,使得未破裂宫外孕的诊断变得可行甚至必要。与此同时,我们对宫外孕自然病史的理解也有所提高。许多早期自行消退的宫外孕患者无需接受手术治疗。随着保守手术方法的引入以及甲氨蝶呤的使用,保留未来生育能力成为可能。在过去110年里,宫外孕治疗的主要成就是死亡率大幅下降:从1880年的72% - 90%降至1990年的0.14%。

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