Grimprel E, Levy C, de La Rocque F, Cohen R, Soubeyrand B, Caulin E, Derrough T, Lecuyer A, d'Athis P, Gaudelus J
Groupe de Pathologie Infectieuse Pédiatrique de la Société Française de Pédiatrie, Paris, France.
Clin Microbiol Infect. 2007 May;13(5):546-9. doi: 10.1111/j.1469-0691.2007.01706.x. Epub 2007 Mar 22.
Paediatric patients hospitalised with varicella (n = 1575) were reported to a French national network between March 2003 and July 2005. Superinfection was identified in 50.3% of cases, principally of skin and soft-tissue (36.5%). The risk of superinfection increased with fever relapse, use of non-steroidal anti-inflammatory drugs, prolonged fever, an age of 1-5 years, and contamination at the childminder's home. Neurological complications were observed in 7.8% of cases, while pulmonary complications were less frequent (3.1%). Forty-nine patients had sequelae and eight patients died. Surveillance should continue in France with a view to the future implementation of a universal vaccination programme.
2003年3月至2005年7月期间,法国一个全国性网络报告了1575名因水痘住院的儿科患者。50.3%的病例出现了二重感染,主要是皮肤和软组织感染(36.5%)。二重感染的风险随着发热复发、使用非甾体抗炎药、发热持续时间延长、1至5岁的年龄以及在托儿所感染而增加。7.8%的病例出现了神经系统并发症,而肺部并发症则较少见(3.1%)。49名患者有后遗症,8名患者死亡。法国应继续进行监测,以期未来实施普遍疫苗接种计划。