Powers J M, Balentine J D, Wiśniewski H M, Terry R D
J Neuropathol Exp Neurol. 1976 Jan;35(1):14-25. doi: 10.1097/00005072-197601000-00002.
The light and electron microscopic features of an unique retroperitoneal ganglioneuroblastoma in a four-year-old female are described. The unprecedented concurrence of Hirano, zebra, membranous cytoplasmic (MCB), and Pick bodies in the same population of neoplastic, sympathetic ganglion cells provides further evidence for their non-specificity. Although the pathogenesis of the membranous cytoplasmic bodies in this tumor is unclear, they ostensibly arise within endoplasmic cisterns, similar to the proposed origin of membranous cytoplasmic bodies in Tay-Sachs disease. Both the apparent continuum between argyrophilic bodies and central chromatolysis, and the incorporation of various cytoplasmic constituents within neurofilamentous proliferations reflect some of the dynamic factors involved in the formation of Pick bodies.
描述了一名4岁女性患者中独特的腹膜后节细胞神经母细胞瘤的光镜和电镜特征。在同一群肿瘤性交感神经节细胞中，同时出现平野小体、斑马小体、膜性胞质体（MCB）和Pick小体，这一前所未有的现象进一步证明了它们的非特异性。尽管该肿瘤中膜性胞质体的发病机制尚不清楚，但它们表面上在内质网池内形成，类似于在泰-萨克斯病中膜性胞质体的推测起源。嗜银小体与中央性染色质溶解之间明显的连续性，以及神经丝增生内各种胞质成分的掺入，反映了参与Pick小体形成的一些动态因素。
