Altgassen Mareike, Phillips Louise, Kopp Ute, Kliegel Matthias
Department of Psychology, University of Zurich, Binzmühlestrasse 14/24, CH-8050 Zürich, Switzerland.
Neuropsychologia. 2007 Jun 11;45(10):2393-7. doi: 10.1016/j.neuropsychologia.2007.02.018. Epub 2007 Mar 2.
The current study investigated the involvement of all four components of Baddeley's [Baddeley, A. D. (2000). The episodic buffer: A new component of working memory? Trends in Cognitive Sciences, 4, 417-423] revised working memory model in deficits of planning accompanying Parkinson's disease (PD). PD resulted in poorer formulation and execution of plans, as measured by the Tower of London task. PD also reduced the efficiency of the episodic buffer and central executive components of working memory, but did not influence storage of verbal or visuospatial information. Planning deficits in PD were particularly linked to problems in integrating multimodal short-term information with long-term memory (episodic buffer). These results emphasize the importance of integrative and executive processing in cognitive problems in PD, rather than simple memory deficits.
当前研究调查了巴德利[巴德利,A.D.(2000年)。情景缓冲器:工作记忆的一个新成分?认知科学趋势,4,417 - 423]修订的工作记忆模型的所有四个成分在帕金森病(PD)伴发的计划缺陷中的作用。通过伦敦塔任务测量,PD导致计划的制定和执行更差。PD还降低了工作记忆的情景缓冲器和中央执行成分的效率,但不影响言语或视觉空间信息的存储。PD中的计划缺陷尤其与多模式短期信息与长期记忆(情景缓冲器)整合方面的问题有关。这些结果强调了整合和执行加工在PD认知问题中的重要性,而非简单的记忆缺陷。