Sammer Gebhard, Reuter Iris, Hullmann Katharina, Kaps Manfred, Vaitl Dieter
Department of Psychology, Justus-Liebig-University of Giessen, Germany.
J Neurol Sci. 2006 Oct 25;248(1-2):115-9. doi: 10.1016/j.jns.2006.05.028. Epub 2006 Jun 12.
Cognitive disturbances are common in Parkinson's disease (PD). Examination of cognitive function often reveals deficits in executive functions, including maintenance and inhibition of attention, flexibility in thinking, and planning. The involvement of the dopaminergic system in cognitive executive functions has been suggested by numerous studies. The aim of the present study was to analyze the effect of cognitive training on cognitive performance of PD-patients (N=26). Half of the patients participated in a cognitive training regimen, while the other patients only received standard treatment. The outcome showed improved performance of the group with cognitive treatment in two executive tasks after the training period, while no improvement was seen in the standard-treatment group. The results indicate that specific training is required for improvement of executive functions, while general rehabilitation is not sufficient. Thus, PD-patients might benefit from a short-term cognitive executive function training program that is tailored to the individual patient's needs.
认知障碍在帕金森病（PD）中很常见。对认知功能的检查常常发现执行功能存在缺陷，包括注意力的维持和抑制、思维灵活性以及计划能力。众多研究表明多巴胺能系统参与了认知执行功能。本研究的目的是分析认知训练对帕金森病患者（N = 26）认知表现的影响。一半患者参加了认知训练方案，而其他患者仅接受标准治疗。结果显示，经过训练期后，接受认知治疗的组在两项执行任务中的表现有所改善，而标准治疗组则没有改善。结果表明，改善执行功能需要特定训练，而一般康复是不够的。因此，帕金森病患者可能会从根据个体患者需求定制的短期认知执行功能训练计划中受益。
