一例并发地中海斑疹热的急性四肢瘫痪病例。

A case of acute quadriplegia complicating Mediterranean spotted fever.

作者信息

Caroleo Santo, Longo Chiara, Pirritano Domenico, Nisticò Rita, Valentino Paola, Iocco Maurizio, Santangelo Ermenegildo, Amantea Bruno

机构信息

Institute of Anaesthesiology, Reanimation and Intensive Care Medicine, University Magna Graecia, Catanzaro, Italy.

出版信息

Clin Neurol Neurosurg. 2007 Jun;109(5):463-5. doi: 10.1016/j.clineuro.2007.02.007. Epub 2007 Mar 26.

DOI:10.1016/j.clineuro.2007.02.007

PMID:17382465

Abstract

Mediterranean spotted fever is a rickettsiosis caused by Rickettsia conorii. Mediterranean spotted fever is considered to be a benign disease, however, approximately 10% of patients present with a severe systemic manifestation in which neurologic involvement occurs. We present a case of an 80-year-old man with a R. conorii infection who developed an acute quadriplegia secondary to an axonal polyneuropathy. The characteristic tache noire was observed on the lateral region of the thigh and elevated IgM antibody titres against R. conorii were detected by an indirect immunofluorescence test.

摘要

地中海斑疹热是由康氏立克次体引起的立克次体病。地中海斑疹热被认为是一种良性疾病，然而，约10%的患者会出现严重的全身表现，其中会发生神经系统受累。我们报告一例80岁男性康氏立克次体感染病例，该患者继发轴索性多发性神经病后出现急性四肢瘫。在大腿外侧观察到特征性的黑色焦痂，通过间接免疫荧光试验检测到针对康氏立克次体的IgM抗体滴度升高。