McKinlay John B, Link Carol L
New England Research Institutes, Watertown, MA 02472, USA.
Eur Urol. 2007 Aug;52(2):389-96. doi: 10.1016/j.eururo.2007.03.013. Epub 2007 Mar 19.
To describe the Boston Area Community Health (BACH) survey, a National Institutes of Health-supported epidemiological study of symptoms suggestive of the following urologic conditions: urinary incontinence, benign prostatic hyperplasia, interstitial cystitis, chronic pelvic pain of bladder origin, prostatitis, hypogonadism, erectile dysfunction, and female sexual dysfunction.
BACH used a two-stage stratified cluster design to recruit a community-based random sample of 5506, divided between males (2301) and females (3205), three racial/ethnic groups (black, Hispanic, and white), and four age groups (30-39, 40-49, 50-59, 60-79 yr). Validated questionnaires were used to collect information on urologic symptoms, comorbidities, prescribed and over-the-counter medications, reproductive history, quality of life, health care utilization, physical activity, depressive symptoms, interpersonal stress, smoking, alcohol use, fluid intake, nutrition, menopausal status, sexual activity, abuse, anthropometrics (measured height, weight, hip and waist circumference, pulse rate, blood pressure), and sociodemographics including country of origin, marital status, employment status, and income. Blood samples were collected from 68% of all subjects.
A large representative community-based sample was successfully recruited to provide both cross-sectional and eventually longitudinal data to address important urologic questions.
BACH has features distinguishing it from most other epidemiological studies in urology. It uses a random community-based sample of people who are racially/ethnically diverse and includes a broad age range (30-79 yr). It includes both males and females The study focuses on symptoms rather than variably defined disease conditions, it is multidisciplinary, and it is designed to become longitudinal.
描述波士顿地区社区健康(BACH)调查,这是一项由美国国立卫生研究院支持的流行病学研究,旨在研究提示以下泌尿系统疾病的症状:尿失禁、良性前列腺增生、间质性膀胱炎、膀胱源性慢性盆腔疼痛、前列腺炎、性腺功能减退、勃起功能障碍和女性性功能障碍。
BACH采用两阶段分层整群设计,招募了一个基于社区的5506人的随机样本,分为男性(2301人)和女性(3205人)、三个种族/族裔群体(黑人、西班牙裔和白人)以及四个年龄组(30 - 39岁、40 - 49岁、50 - 59岁、60 - 79岁)。使用经过验证的问卷收集有关泌尿系统症状、合并症、处方药和非处方药、生殖史、生活质量、医疗保健利用、身体活动、抑郁症状、人际压力、吸烟、饮酒、液体摄入量、营养、绝经状态、性活动、虐待、人体测量学(测量身高、体重、臀围和腰围、脉搏率、血压)以及社会人口统计学信息,包括原籍国、婚姻状况、就业状况和收入。从所有受试者的68%中采集了血样。
成功招募了一个具有代表性的大型社区样本,以提供横断面数据并最终提供纵向数据,以解决重要的泌尿系统问题。
BACH具有一些使其有别于大多数其他泌尿外科流行病学研究的特征。它使用基于社区的随机样本,样本涵盖不同种族/族裔的人群,年龄范围广泛(30 - 79岁)。研究对象包括男性和女性。该研究关注症状而非定义各异的疾病状况,具有多学科性质,并且设计为纵向研究。