Barry Michael J, Link Carol L, McNaughton-Collins Mary F, McKinlay John B
Medical Practices Evaluation Center, Massachusetts General Hospital, Boston, MA 02114, USA.
BJU Int. 2008 Jan;101(1):45-51. doi: 10.1111/j.1464-410X.2007.07191.x. Epub 2007 Sep 13.
To define the prevalence and overlap of symptom patterns traditionally associated with benign prostatic hyperplasia, chronic prostatitis/chronic pelvic pain syndrome, interstitial cystitis/painful bladder syndrome, and incontinence among men and women in a racially and ethnically diverse, community-based population.
In all, 5506 men and women aged 30-79 years were recruited to participate in the Boston Area Community Health Survey, using a stratified-cluster sampling technique to obtain roughly similar representative samples by age group, gender and race/ethnicity (White, Black, Hispanic). Survey data were collected by bilingual interviewers in subjects' homes. Scales measuring symptom patterns were derived from validated instruments, with minor changes to eliminate different recall periods and overlap in items that might have confused subjects.
About a quarter of men and women of all ages met the definition for one or more of the target symptom patterns; there was no significant variation in the prevalence of any of the symptom patterns by race/ethnicity. Overall, approximately 16% of men and women had one symptom pattern, while 7% had overlap patterns. Except for urinary incontinence and interstitial cystitis/painful bladder syndrome in both men and women, the prevalence of all symptom complexes were associated with one another significantly more often that would be expected by chance.
Overlapping patterns of lower urinary tract symptoms and pelvic pain are common. These overlapping patterns present challenges for clinical practice and research, and require further investigation of their causes, diagnosis and optimum treatment.
确定在一个种族和民族多样化的社区人群中，男性和女性中传统上与良性前列腺增生、慢性前列腺炎/慢性盆腔疼痛综合征、间质性膀胱炎/疼痛性膀胱综合征以及尿失禁相关的症状模式的患病率和重叠情况。
总共招募了5506名年龄在30 - 79岁之间的男性和女性参与波士顿地区社区健康调查，采用分层整群抽样技术，按年龄组、性别和种族/民族（白人、黑人、西班牙裔）获取大致相似的代表性样本。调查数据由双语访员在受试者家中收集。测量症状模式的量表源自经过验证的工具，并做了细微改动以消除不同的回忆期以及可能使受试者混淆的项目重叠问题。
所有年龄段的男性和女性中约四分之一符合一种或多种目标症状模式的定义；任何症状模式的患病率在种族/民族方面均无显著差异。总体而言，约16%的男性和女性有一种症状模式，而7%有重叠模式。除了男性和女性的尿失禁以及间质性膀胱炎/疼痛性膀胱综合征外，所有症状组合的患病率相互之间的关联显著高于偶然预期。
下尿路症状和盆腔疼痛的重叠模式很常见。这些重叠模式给临床实践和研究带来了挑战，需要进一步研究其病因、诊断和最佳治疗方法。
