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血清素综合征

Serotonin syndrome.

作者信息

Evans Charlotte Elizabeth, Sebastian Joseph

机构信息

The Royal Melbourne Hospital Intensive Care Unit, Melbourne, Victoria, Australia.

出版信息

Emerg Med J. 2007 Apr;24(4):e20. doi: 10.1136/emj.2006.040550.

DOI:10.1136/emj.2006.040550
PMID:17384366
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2658256/
Abstract

Serotonin syndrome is an under-reported and under-recognised condition that occurs on administration of selective serotonin re-uptake inhibitors alone, or in combination with other medication known to increase levels of 5-hydroxytryptamine. This case report demonstrates signs and symptoms associated with their overdose and illustrates the importance of recognition of this syndrome to instigate appropriate treatment for the patient.

摘要

血清素综合征是一种报告不足且认识不足的病症,它可单独发生于使用选择性血清素再摄取抑制剂时,或与已知会增加5-羟色胺水平的其他药物联合使用时。本病例报告展示了与药物过量相关的体征和症状,并说明了识别该综合征对为患者采取适当治疗措施的重要性。

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本文引用的文献

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Serotonin syndrome: a brief review.血清素综合征:简要综述。
CMAJ. 2003 May 27;168(11):1439-42.
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Serotonin syndrome treated with chlorpromazine.
J Clin Psychopharmacol. 1997 Apr;17(2):128-9. doi: 10.1097/00004714-199704000-00017.
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Serotonin syndrome. Presentation of 2 cases and review of the literature.血清素综合征。2例病例报告及文献综述。
Medicine (Baltimore). 2000 Jul;79(4):201-9. doi: 10.1097/00005792-200007000-00001.
4
Treatment of the serotonin syndrome with cyproheptadine.用赛庚啶治疗血清素综合征。
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Serotonin syndrome. A clinical update.血清素综合征。临床最新进展。
Crit Care Clin. 1997 Oct;13(4):763-83. doi: 10.1016/s0749-0704(05)70368-7.