Cullen J F, Por Y M
Neuro-Ophthalmology Service, Singapore National Eye Centre, Level 8, 11 Third Hospital Avenue, Singapore 168751.
Singapore Med J. 2007 Apr;48(4):281-6.
The commonest cause of an optic neuropathy in Singapore is ischaemia, and ischaemic optic neuropathy (ION) is one of the commonest causes of permanent loss of vision in elderly patients, especially in those with diabetes mellitus, hypertension and hyperlipidaemia. ION in our practice is almost invariably of the anterior variety and non-arteritic in origin, i.e. NA-AION. Posterior ION comprises less than two percent of our cases. Three patients with different patterns of NA-AION are described, and in the discussion, how the condition can be distinguished clinically from optic neuritis. With respect to posterior ION, the necessity of excluding a compressive cause before this diagnosis can be made is emphasised.
在新加坡，视神经病变最常见的病因是缺血，而缺血性视神经病变（ION）是老年患者永久性视力丧失的常见病因之一，尤其是患有糖尿病、高血压和高脂血症的患者。在我们的临床实践中，ION几乎均为前部类型且病因是非动脉性的，即非动脉炎性前部缺血性视神经病变（NA-AION）。后部缺血性视神经病变（Posterior ION）在我们的病例中占比不到2%。本文描述了3例具有不同模式的NA-AION患者，并在讨论中阐述了该疾病在临床上如何与视神经炎相鉴别。关于后部ION，强调在做出该诊断之前必须排除压迫性病因。
