铑催化的α-芳基-α-重氮酮的分子内C-H插入反应
Rhodium-catalyzed intramolecular C-H insertion of alpha-aryl-alpha-diazo ketones.
作者信息
Taber Douglass F, Tian Weiwei
机构信息
Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716, USA.
出版信息
J Org Chem. 2007 Apr 27;72(9):3207-10. doi: 10.1021/jo0624694. Epub 2007 Mar 27.
Abstract
Direct diazo transfer proceeds smoothly with alpha-aryl ketones. The derived alpha-aryl-alpha-diazo ketones cyclize efficiently with Rh catalysis to give the corresponding alpha-aryl cyclopentanones.
摘要
直接重氮转移反应在α-芳基酮存在下顺利进行。衍生得到的α-芳基-α-重氮酮在铑催化下能有效环化，生成相应的α-芳基环戊酮。
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