Rannou F, Boutron I, Jardinaud-Lopez M, Meric G, Revel M, Fermanian J, Poiraudeau S
Service de Médecine Physique et Réadaptation, Hôpital Cochin (AP-HP), Université Paris 5, Institut Fédératif de Recherche sur le Handicap (IFR 25) INSERM, Paris, France.
Osteoarthritis Cartilage. 2007 Sep;15(9):1013-8. doi: 10.1016/j.joca.2007.02.012. Epub 2007 Mar 26.
To assess the relevance of using the aggregate physical component score (PCS) and mental component score (MCS) of the Medical Outcomes Study 36-item Short Form Health Survey (SF-36) for patients with knee and hip osteoarthritis (OA).
We conducted a cross-sectional national survey in a primary care setting in France. A total of 1474 general practitioners enrolled 4183 patients with hip or knee OA. Construct validity of PCS and MCS was assessed by convergent and divergent validity and factor analysis.
Records of 4133 patients (98.8%) were analyzed (2540 knee, 1593 hip OA). PCS mean scores were 32.0+/-8.4 and 31.8+/-8.4 and MCS scores 47.1+/-11.0 and 46.8+/-11.1, for knee and hip OA, respectively. Acceptable convergent and divergent validity was observed, and correlation between PCS and MCS mean scores was low (r=0.14). However, factor analysis performed on the eight subscale scores failed to support the use of PCS and MCS aggregate scores. It extracted two factors which were similar for both OA types and differed from the a priori stratification. Scores for two subscales usually attributed to MCS - emotional role and social functioning - were shared between factors, and scores for another subscale - general health perception - usually belonging to the PCS was in the mental component factor.
Our results suggest that aggregate scores from the PCS and MCS of the SF-36 as they are currently defined may not be optimal for used in hip and knee OA patients to assess health-related quality of life.
评估医学结局研究简明健康调查36项量表(SF - 36)的总体身体成分得分(PCS)和心理成分得分(MCS)用于髋膝关节骨关节炎(OA)患者的相关性。
我们在法国的基层医疗环境中进行了一项横断面全国性调查。共有1474名全科医生纳入了4183例髋或膝关节OA患者。通过收敛效度、区分效度和因子分析评估PCS和MCS的结构效度。
分析了4133例患者(98.8%)的记录(2540例膝关节OA,1593例髋关节OA)。膝关节OA和髋关节OA的PCS平均得分分别为32.0±8.4和31.8±8.4,MCS得分分别为47.1±11.0和46.8±11.1。观察到可接受的收敛效度和区分效度,且PCS和MCS平均得分之间的相关性较低(r = 0.14)。然而,对八个子量表得分进行的因子分析未能支持使用PCS和MCS总分。它提取了两个因子,这两个因子在两种OA类型中相似,且与先验分层不同。通常归因于MCS的两个子量表——情感角色和社会功能——的得分在因子之间共享,而另一个通常属于PCS的子量表——总体健康感知——的得分在心理成分因子中。
我们的结果表明,目前定义的SF - 36的PCS和MCS总分可能并非评估髋膝关节OA患者健康相关生活质量的最佳选择。