Department of Biology, Concordia University, Montreal, Quebec, Canada.
PLoS One. 2007 Mar 28;2(3):e325. doi: 10.1371/journal.pone.0000325.
DNA barcodes have achieved prominence as a tool for species-level identifications. Consequently, there is a rapidly growing database of these short sequences from a wide variety of taxa. In this study, we have analyzed the correlation between the nucleotide content of the short DNA barcode sequences and the genomes from which they are derived. Our results show that such short sequences can yield important, and surprisingly accurate, information about the composition of the entire genome. In other words, for unsequenced genomes, the DNA barcodes can provide a quick preview of the whole genome composition.
DNA 条形码已经成为物种水平鉴定的重要工具。因此,各种分类单元的这些短序列的数据库正在迅速增长。在这项研究中,我们分析了短 DNA 条形码序列的核苷酸含量与它们所衍生的基因组之间的相关性。我们的结果表明,这些短序列可以提供关于整个基因组组成的重要且令人惊讶的准确信息。换句话说,对于未测序的基因组,DNA 条形码可以快速预览整个基因组的组成。