Tarozzi Marco, Demarosi Federica, Lodi Giovanni, Sardella Andrea, Carrassi Antonio
Unit of Oral Pathology and Medicine, School of Dentistry, University of Milan, Milan, Italy.
J Oral Pathol Med. 2007 Apr;36(4):252-4. doi: 10.1111/j.1600-0714.2007.00486.x.
Small cell carcinoma (SCC) is a malignancy that mainly occurs in the lung, with primary lesions in the head and neck being very rare. This neoplasm has an aggressive growth pattern, high recurrence rate, and tendency to metastasize to other sites via the lymphatics and bloodstream. The prognosis of patients with SCC is poor, as the 5-year survival is only 13%. Treatment options include surgical excision, multiple-agent chemotherapy, and radiation therapy. We report a rare case of primary SCC of the nasal cavity presenting as a lesion of the hard palate and describe its clinical, histologic, and immunohistochemical features.
小细胞癌（SCC）是一种主要发生于肺部的恶性肿瘤，原发于头颈部的病变极为罕见。这种肿瘤具有侵袭性生长模式、高复发率，且有通过淋巴管和血流转移至其他部位的倾向。SCC患者的预后较差，5年生存率仅为13%。治疗选择包括手术切除、多药化疗和放射治疗。我们报告一例罕见的鼻腔原发性SCC，表现为硬腭病变，并描述其临床、组织学和免疫组化特征。
