Rousculp Matthew D, Long Stacey R, Wang Shaohung, Schoenfeld Michael J, Meadows Eric S
Lilly Research Laboratories, Indianapolis, IN, USA.
Value Health. 2007 Mar-Apr;10(2):144-52. doi: 10.1111/j.1524-4733.2006.00161.x.
There are limited studies concerning the economic burden of osteoporosis in the Medicaid population. This study estimated the direct cost of osteoporosis-related fractures (OPFx) to state Medicaid budgets.
This retrospective analysis utilized Medicaid claims databases from three states, which included approximately 8 million Medicaid recipients. The study sample had at least one claim for an osteoporosis diagnosis (733.0x) between January 1, 2000 and December 31, 2001. Beneficiaries with a fracture and a diagnosis of osteoporosis were assigned to the case cohort. A propensity score-based matching method was used to select a cohort of controls with osteoporosis but without a fracture. An exponential conditional mean model was used to estimate the incremental annual cost associated with fractures.
The study cohort (n = 7626) and a 1:1 matched control group were identified. The study cohort was 85.8% female, had an average age of 65 years, were 53.2% white, and 48.9% were eligible for Medicare. There were significant increases (all P < 0.05) from the preperiod to study period for this cohort in the proportion that had at least one hospital admission (14.0% vs. 26.5%), nursing home admission (9.2% vs. 17.2%), home health (39.1% vs. 49.3%), or emergency room visit (21.3% vs. 31.9%). In contrast, the control cohort had very little increase in utilization. The regression-adjusted incremental cost for osteoporosis-related expenses in the year after fracture was estimated at $4007 per patient. The estimated incremental cost was $5370 for the subset of patients who were eligible for Medicare.
The economic burden of osteoporosis-related fractures on state Medicaid budgets is substantial.
关于医疗补助人群中骨质疏松症经济负担的研究有限。本研究估算了与骨质疏松症相关骨折(OPFx)给各州医疗补助预算带来的直接成本。
这项回顾性分析利用了来自三个州的医疗补助理赔数据库,其中包括约800万医疗补助受益对象。研究样本在2000年1月1日至2001年12月31日期间至少有一项骨质疏松症诊断(733.0x)理赔记录。有骨折且被诊断为骨质疏松症的受益人被纳入病例队列。采用基于倾向评分的匹配方法选择一组患有骨质疏松症但未发生骨折的对照人群。使用指数条件均值模型估算与骨折相关的年度增量成本。
确定了研究队列(n = 7626)和1:1匹配的对照组。研究队列中女性占85.8%,平均年龄为65岁,53.2%为白人,48.9%符合医疗保险资格。该队列从前期到研究期,至少有一次住院(14.0%对26.5%)、入住疗养院(9.2%对17.2%)、接受家庭健康护理(39.1%对49.3%)或急诊就诊(21.3%对31.9%)的比例均有显著增加(所有P < 0.05)。相比之下,对照队列的利用率几乎没有增加。骨折后一年与骨质疏松症相关费用的回归调整增量成本估计为每位患者4007美元。对于符合医疗保险资格的患者子集,估计增量成本为5370美元。
骨质疏松症相关骨折给各州医疗补助预算带来的经济负担巨大。