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双相性肺母细胞瘤:一例报告

Biphasic pulmonary blastoma: report of a case.

作者信息

Iwata Takashi, Nishiyama Noritoshi, Inoue Kiyotoshi, Kawata Yasuhiro, Izumi Nobuhiro, Tsukioka Takuma, Shinkawa Kanji, Suehiro Shigefumi

机构信息

Department of Thoracic Surgery, Osaka City University Hospital, Osaka, Japan.

出版信息

Ann Thorac Cardiovasc Surg. 2007 Feb;13(1):40-3.

Abstract

A 73-year-old male presented with bloody sputa for a month. Chest computed tomography (CT) showed a large mass about 7 cm in diameter in the right lower lobe. Bronchoscopic curette cytology revealed class V and a suspected adenocarcinoma, although a systemic evaluation demonstrated no metastatic lesion. The patient underwent a right lower lobectomy and mediastinal dissection. A biphasic pulmonary blastoma was histologically diagnosed by a characteristic finding that it was mainly constituted of immature tumor tissue that had both epithelial and mesenchymal components. No mediastinal lymph node metastasis was proven. Stage T2N0M0 disease was diagnosed, and the patient chose not to undergo postoperative adjuvant chemotherapy; he remains well without recurrence 36 months after the operation.

摘要

一名73岁男性出现血痰1个月。胸部计算机断层扫描(CT)显示右下叶有一个直径约7厘米的大肿块。支气管镜刮除细胞学检查显示为V级,疑似腺癌,尽管全身评估未发现转移病灶。患者接受了右下叶切除术和纵隔清扫术。组织学诊断为双相性肺母细胞瘤,其特征性表现为主要由具有上皮和间叶成分的未成熟肿瘤组织构成。未证实有纵隔淋巴结转移。诊断为T2N0M0期疾病,患者选择不接受术后辅助化疗;术后36个月,他情况良好,无复发。

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