LaForce W R, Brudno D S, Kanto W P, Karp W B
Medical College of Georgia, Section of Neonatology, Augusta 30912.
Ann Clin Lab Sci. 1992 Jan-Feb;22(1):30-3.
A viscoelastometer, the SonoClot Coagulation Analyzer, has been proposed for use in the evaluation of platelet function. The purpose of this study was to evaluate systematically this instrument when used with whole blood. Under laboratory conditions, the coefficient of variation (cv) of determinations of whole blood activated clotting time (ACT) on the instrument was approximately 7.0 percent. In contrast, the cv of measurements on whole blood related to the graphic events associated with clot formation ranged from 9.2 to 41.7 percent. Because of the large and variable cvs associated with these measurements of clotting, the SonoClot Analyzer cannot presently be recommended for use in studies designed to examine quantitatively the clotting function in whole blood.
一种粘弹性测定仪，即声凝凝血分析仪，已被提议用于评估血小板功能。本研究的目的是系统评估该仪器在全血检测中的应用情况。在实验室条件下，该仪器对全血活化凝血时间（ACT）测定的变异系数（cv）约为7.0%。相比之下，与凝血形成相关的图形事件的全血测量cv范围为9.2%至41.7%。由于这些凝血测量的cv值较大且变化不定，目前不建议将声凝分析仪用于旨在定量检测全血凝血功能的研究。
