Blifeld C, Courtney J T, Gross J R
Ann Clin Lab Sci. 1986 Sep-Oct;16(5):373-9.
The Sonoclot, a simple viscoelastometer, measures changes in the viscoelastic properties of plasma as it is recalcified. Platelet rich plasma (PRP) and platelet poor plasma (PPP) each have characteristic Sonoclot tracings. This technique was applied to evaluate the coagulability and platelet function, specifically, in PRP prepared from 53 normal term newborn cord bloods and whole blood from 17 very low birth weight premature infants. These values were compared to each other and to those previously reported adult control values obtained by one of the authors (C.B.). The cord PRP samples had shorter time related parameters than adult controls. The values from premature infants were suggestive of diminished platelet function when compared to cord values but were similar to adult values. This technique allows the use of small sample volumes, the minimization of the introduction of infection risks, and avoids manipulation of fragile, very premature infants.
Sonoclot是一种简单的粘弹性测定仪，可测量血浆重新钙化时其粘弹性特性的变化。富血小板血浆（PRP）和贫血小板血浆（PPP）各自具有特征性的Sonoclot描记图。该技术被用于评估53例足月正常新生儿脐带血制备的PRP以及17例极低出生体重早产儿全血的凝血能力和血小板功能。将这些值相互比较，并与其中一位作者（C.B.）先前报告的成人对照值进行比较。脐带PRP样本的时间相关参数比成人对照短。与脐带值相比，早产儿的值提示血小板功能降低，但与成人值相似。该技术允许使用少量样本，将感染风险的引入降至最低，并且避免了对脆弱的极早产儿进行操作。
