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国际虫媒病毒研究。

International arbovirus research.

作者信息

Casals J

出版信息

Med Biol. 1975 Oct;53(5):249-58.

PMID:173936
Abstract

International cooperation in arbovirus research became increasingly prominent shortly after it was found in the early 1940's, that antigenic relationships existed among certain viruses isolated in different areas of thw world. The interest of a number of scientists and of a private organization led to the establishment of an international information exchange and to the preparation of an international catalogue of arboviruses including certain other viruses of vertebrates. International cooperation was fostered by the interest taken in these agents by the World Health Organization and the creation by this agency of an international net of collaborating laboratories with assigned areas of the world. A number of recent problems have been revealed and solved, or partly solved by this international effort, among which are questions relating to: the Marburg agent disease, the existence of an antigenic relationship between rabies virus and some arboviruses, aspects of the ecology or viruses in the California, Uukuniemi and Kemerovo groups, as well as several unanticipated antigenic relationships among viruses. Numerous questions still remain the solution of which might be expedited by continued and increased cooperative international effort such as overwintering or survival of viruses under unfavorable circumstances, pathogenic potential for man and domestic animals of certain viruses, role on chronic illnesses, establishment of the etiology of certain diseases and investigations of the basic properties of viruses, particularly of the Bunyaviridae.

摘要

在20世纪40年代初发现世界不同地区分离出的某些病毒之间存在抗原关系后不久,虫媒病毒研究的国际合作变得日益突出。一些科学家和一个私人组织的兴趣促成了国际信息交流的建立以及虫媒病毒国际目录的编制,该目录还包括某些其他脊椎动物病毒。世界卫生组织对这些病原体的关注以及该机构建立的在世界指定地区设有合作实验室的国际网络促进了国际合作。通过这种国际努力揭示并解决了或部分解决了一些近期问题,其中包括与以下方面有关的问题:马尔堡病原体疾病、狂犬病病毒与某些虫媒病毒之间抗原关系的存在、加利福尼亚、乌昆耶米和克麦罗沃病毒群中病毒的生态学方面,以及病毒之间一些意外的抗原关系。仍然存在许多问题,通过持续加强国际合作努力,例如病毒在不利环境下的越冬或存活、某些病毒对人和家畜的致病潜力、在慢性病中的作用、某些疾病病因的确定以及病毒基本特性的研究,特别是布尼亚病毒科病毒基本特性的研究,这些问题的解决可能会加快。

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