Redd John T, Baumbach Joan, Kohn William, Nainan Omana, Khristova Marina, Williams Ian
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
J Infect Dis. 2007 May 1;195(9):1311-4. doi: 10.1086/513435. Epub 2007 Mar 21.
We used molecular epidemiologic techniques to document patient-to-patient transmission of hepatitis B virus (HBV) between 2 outpatient oral surgery patients operated on 161 min apart. Serological testing of 25 (93%) of 27 patients operated on after the source patient revealed that 19 (76%) of 25 were previously immune to HBV; no additional cases were identified. We found no deficiencies in infection control practices. Transmission may have been limited by the high prevalence (64%) of patients vaccinated against HBV. To our knowledge, this is the first documented case of patient-to-patient transmission of a bloodborne pathogen in a dental setting in the United States.
我们运用分子流行病学技术，记录了在间隔161分钟接受手术的两名门诊口腔外科患者之间乙肝病毒（HBV）的患者间传播情况。对源患者之后接受手术的27名患者中的25名（93%）进行血清学检测发现，这25名患者中有19名（76%）之前对HBV免疫；未发现其他病例。我们未发现感染控制措施存在缺陷。传播可能因接种HBV疫苗的患者比例较高（64%）而受到限制。据我们所知，这是美国牙科环境中首例有记录的血源性病原体患者间传播病例。
