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黑腹果蝇黑色突变体和黑色抑制突变体中的β-丙氨酸转氨酶活性

Beta-alanine transaminase activity in black and suppressor of black mutations of Drosophila melanogaster.

作者信息

Weber J P, Bolin R J, Hixon M S, Sherald A F

机构信息

Department of Chemistry, George Mason University, Fairfax, VA 22030.

出版信息

Biochim Biophys Acta. 1992 Jan 23;1115(3):181-6. doi: 10.1016/0304-4165(92)90051-u.

DOI:10.1016/0304-4165(92)90051-u
PMID:1739732
Abstract

An assay for beta-alanine transaminase activity in extracts of Drosophila melanogaster has been developed. By use of this assay, the levels of beta-alanine transaminase activity in several strains of flies has been examined as a function of developmental age. The black mutation shows elevated levels of activity compared to wild type, while suppressor of black strains show decreased levels compared to wild type.

摘要

已开发出一种用于检测黑腹果蝇提取物中β-丙氨酸转氨酶活性的测定方法。通过使用该测定方法,已研究了几种果蝇品系中β-丙氨酸转氨酶活性水平随发育年龄的变化情况。与野生型相比,黑色突变体显示出较高的活性水平,而黑色品系的抑制子与野生型相比则显示出较低的活性水平。

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Beta-alanine transaminase activity in black and suppressor of black mutations of Drosophila melanogaster.黑腹果蝇黑色突变体和黑色抑制突变体中的β-丙氨酸转氨酶活性
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Analysis of pyrimidine catabolism in Drosophila melanogaster using epistatic interactions with mutations of pyrimidine biosynthesis and beta-alanine metabolism.利用与嘧啶生物合成和β-丙氨酸代谢突变的上位相互作用分析黑腹果蝇中的嘧啶分解代谢。
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3
The dominant mutation Suppressor of black indicates that de novo pyrimidine biosynthesis is involved in the Drosophila tan pigmentation pathway.
黑色抑制因子的显性突变表明,从头嘧啶生物合成参与了果蝇棕褐色色素沉着途径。
Mol Gen Genet. 1993 Nov;241(3-4):335-40. doi: 10.1007/BF00284686.