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黑腹果蝇黑色突变的基因间抑制作用。

Intergenic suppression of the black mutation of Drosophila melanogaster.

作者信息

Sherald A F

出版信息

Mol Gen Genet. 1981;183(1):102-6. doi: 10.1007/BF00270146.

DOI:10.1007/BF00270146
PMID:6799739
Abstract

Five X-linked, recessive alleles were isolated which suppressed both the pupal and adult coloration phenotypes of the black mutation. Electron micrographs of shed puparia revealed that the aberrant sclerotization of the black cuticle is also suppressed. Amino acid analysis indicated that suppression is associated with an increased concentration of beta-alanine, an amino acid known to be deficient in black. The suppressor locus mapped at the tip of the X, to the right of scute, and intragenic complementation was observed among the alleles.

摘要

分离出了五个X连锁隐性等位基因,它们抑制了黑色突变的蛹期和成虫体色表型。脱落蛹壳的电子显微镜照片显示,黑色表皮异常的硬化也受到了抑制。氨基酸分析表明,抑制作用与β-丙氨酸浓度的增加有关,β-丙氨酸是一种已知在黑色突变体中缺乏的氨基酸。抑制基因座定位于X染色体的末端,在scute的右侧,并且在这些等位基因之间观察到了基因内互补。

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本文引用的文献

1
Beta-Alanine Utilization of Ebony and Non-ebony Drosophila melanogaster.黑木果蝇和非黑木果蝇的β-丙氨酸利用。
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The induction of mosaic and complete dumpy mutants in Drosophila melanogaster with ethyl methanesulfonate.用甲磺酸乙酯诱导黑腹果蝇中的镶嵌和完全短粗突变体。
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